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Lignocellulase Formation, Regulation, and Secretion Mechanisms in Hypocrea jecorina (Trichoderma reesei) and Other Filamentous Fungi

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Fungal Cellulolytic Enzymes

Abstract

Trichoderma reesei is the anamorph form of Hypocrea jecorina (H. jecorina) and belongs to a soft rot ascomycetal fungus that is used in commercial applications, such as the production of enzymes; this fungus is an efficient cell factory for protein production, a property that is exploited by the enzyme industry. The most important property of H. jecorina for commercial applications is that it can secrete a variety of cellulases involved in lignocellulose hydrolysis, a property that has made H. jecorina the most widely used cellulase in the world, producing filamentous fungi for research and other applications. In this chapter, the functions of transcription factors that regulate cellulase and hemicellulase will be introduced, and the expression of cellulases and hemicellulases regulated by chromatin remodeling will also be discussed. Furthermore, the transcriptional regulation of cellulase and hemicellulase in H. jecorina by external signals will be discussed.

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Acknowledgments

This work was supported by National Natural Science Foundation of China (NO.31570040), the Fundamental Research Funds of Shandong University (No.2016JC031), and the 111 Project (B16030).

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Authors and Affiliations

  1. State Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, China

    Yi Jiang, Wei Guo, Ruiqin Zhang, Fengxin Liu, Nan Zhang & Xu Fang

  2. Department of Food Engineering, Rongcheng College, Harbin University of Science and Technology, Harbin, 150080, China

    Kuimei Liu

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  1. State Key Laboratory of Microbial Technology, Shandong University, Jinan, Shandong, China

    Xu Fang

  2. State Key Laboratory of Microbial Technology, Shandong University, Jinan, Shandong, China

    Yinbo Qu

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Jiang, Y. et al. (2018). Lignocellulase Formation, Regulation, and Secretion Mechanisms in Hypocrea jecorina (Trichoderma reesei) and Other Filamentous Fungi. In: Fang, X., Qu, Y. (eds) Fungal Cellulolytic Enzymes. Springer, Singapore. https://doi.org/10.1007/978-981-13-0749-2_3

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