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Medical Applications of Collagen and Hyaluronan in Regenerative Medicine

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Novel Biomaterials for Regenerative Medicine

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1077))

Abstract

In order to develop and commercialize for the regenerative medicinal products, smart biomaterials with biocompatibility must be needed. In this chapter, we introduce collagen and hyaluronic acid (HA) as extracellular matrix as well as deal with the molecular mechanism as microenvironment, mechanistic effects, and gene expression. Application of collagen and HA have been reviewed in the area of orthopedics, orthopedics, ophthalmology, dermatology and plastic surgery. Finally, the ongoing and commercial products of collagen and HA for regenerative medicine have been introduced.

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Authors and Affiliations

  1. Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan

    Lynn L. H. Huang, Ying-Hui Amy Chen, Zheng-Ying Zhuo, Jhih-Ying Lin, You-Xin Lin, Jian-Ting Jiang, Chao-Hsung Zhuang, Yi-Ching Wang & Hanhhieu Nguyendac

  2. Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan

    Lynn L. H. Huang

  3. Research Center of Excellence in Regenerative Medicine, National Cheng Kung University, Tainan, Taiwan

    Lynn L. H. Huang, Ya-Ting Hsieh, Chia-Ling Yang, Wei-Ting Chen, Kai-Wei Lin & Wen-Lung Liu

  4. International Research Center for Wound Repair and Regeneration, Tainan, Taiwan

    Lynn L. H. Huang

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Correspondence to Lynn L. H. Huang .

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    Heung Jae Chun

  2. Korea Institute of Science and Technology, Seoul, Korea (Republic of)

    Kwideok Park

  3. Korea Institute of Radiological and Medical Sciences, Seoul, Korea (Republic of)

    Chun-Ho Kim

  4. Chonbuk National University, Jeonju, Korea (Republic of)

    Gilson Khang

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Huang, L.L.H. et al. (2018). Medical Applications of Collagen and Hyaluronan in Regenerative Medicine. In: Chun, H., Park, K., Kim, CH., Khang, G. (eds) Novel Biomaterials for Regenerative Medicine. Advances in Experimental Medicine and Biology, vol 1077. Springer, Singapore. https://doi.org/10.1007/978-981-13-0947-2_15

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