Abstract
Ectopia lentis (EL) is the dislocation of the lens from its normal position, which is maintained by the zonular filaments. Lens subluxation refers to a partial displacement of the lens. Lens displacement can be associated with various complications such as refractive error, diplopia, cataract, leakage of lens proteins into the vitreous with consequent inflammation of the vitreous, and chorioretinitis. Displacement into the anterior chamber may result in papillary block and glaucoma. EL can arise due to hereditary factors or may be secondary to various conditions including trauma, large eyeball, cataracts, pseudoexfoliation, etc. Hereditary EL can be isolated or associated with systemic manifestations. It is most commonly found in Marfan syndrome and also in syndromes such as Weill-Marchesani and Ehlers-Danlos and some metabolic disorders.
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Kannabiran, C. (2019). Genetics of Ectopia Lentis. In: Genetics of Eye Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-13-7146-2_3
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DOI: https://doi.org/10.1007/978-981-13-7146-2_3
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