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Functionalization of Carbon Nanotubes

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Carbon Nanotubes for Targeted Drug Delivery

Part of the book series: SpringerBriefs in Applied Sciences and Technology ((BRIEFSAPPLSCIENCES))

Abstract

Functionalization is defined as the modification of carbon nanotubes (CNTs) in which the preferred functional group drug molecule where the desired drug molecule or a functional group is introduced over the CNTs wall for several applications (Lay et al., Expert Rev Med Devices 8:561–566, 2011).

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References

  • H. Ago, K. Petritsch, M.S. Shaffer, A.H. Windle, R.H. Friend, Composites of carbon nanotubes and conjugated polymers for photovoltaic devices. Adv. Mater. 11, 1281–1285 (1999)

    Article  CAS  Google Scholar 

  • K. Balasubramanian, M. Burghard, Chemically functionalized carbon nanotubes. Small 1, 180–192 (2005)

    Article  CAS  Google Scholar 

  • P.W. Barone, M.S. Strano, Reversible control of carbon nanotube aggregation for a glucose affinity sensor. Angew. Chem. Int. Edn. 45, 8138–8141 (2006)

    Article  CAS  Google Scholar 

  • K. Besteman, J.-O. Lee, F.G. Wiertz, H.A. Heering, C. Dekker, Enzyme-coated carbon nanotubes as single-molecule biosensors. Nano Lett. 3, 727–730 (2003)

    Article  CAS  Google Scholar 

  • P. Bilalis, D. Katsigiannopoulos, A. Avgeropoulos, G. Sakellariou, Non-covalent functionalization of carbon nanotubes with polymers. Rsc Adv. 4, 2911–2934 (2014)

    Article  CAS  Google Scholar 

  • G. Chambers, C. Carroll, G.F. Farrell, A.B. Dalton, M. McNamara, in het M. Panhuis, H.J. Byrne, Characterization of the interaction of gamma cyclodextrin with single-walled carbon nanotubes. Nano Lett. 3, 843–846 (2003)

    Google Scholar 

  • R.J. Chen, Y. Zhang, D. Wang, H. Dai, Noncovalent sidewall functionalization of single-walled carbon nanotubes for protein immobilization. J. Am. Chem. Soc. 123, 3838–3839 (2001)

    Article  CAS  Google Scholar 

  • R. Czerw, Z. Guo, P.M. Ajayan, Y.-P. Sun, D.L. Carroll, Organization of polymers onto carbon nanotubes: a route to nanoscale assembly. Nano Lett. 1, 423–427 (2001)

    Article  CAS  Google Scholar 

  • H. Dodziuk, A. Ejchart, W. Anczewski, H. Ueda, E. Krinichnaya, G. Dolgonos, W. Kutner, Water solubilization, determination of the number of different types of single-wall carbon nanotubes and their partial separation with respect to diameters by complexation with η-cyclodextrin. Chem. Commun. 8, 986–987 (2003)

    Article  Google Scholar 

  • K. Fu, W. Huang, Y. Lin, D. Zhang, T.W. Hanks, A.M. Rao, Y.-P. Suna, Functionalization of carbon nanotubes with bovine serum albumin in homogeneous aqueous solution. J. Nanosci. Nanotechnol. 2, 457–461 (2002a)

    Article  CAS  Google Scholar 

  • K. Fu, A. Kitaygorodskiy, A.M. Rao, Y.-P. Sun, Deuterium attachment to carbon nanotubes in solution. Nano Lett. 2, 1165–1168 (2002b)

    Article  CAS  Google Scholar 

  • A.P. Goodwin, S.M. Tabakman, K. Welsher, S.P. Sherlock, G. Prencipe, H. Dai, Phospholipid—dextran with a single coupling point: a useful amphiphile for functionalization of nanomaterials. J. Am. Chem. Soc. 131, 289–296 (2008)

    Article  Google Scholar 

  • V. Gupta, O. Moradi, I. Tyagi, S. Agarwal, H. Sadegh, R. Shahryari-Ghoshekandi, A. Makhlouf, M. Goodarzi, A. Garshasbi, Study on the removal of heavy metal ions from industry waste by carbon nanotubes: effect of the surface modification: a review. Crit. Rev. Environ. Sci. Technol. 46, 93–118 (2016)

    Article  CAS  Google Scholar 

  • D.E. Hill, Y. Lin, L.F. Allard, Y.-P. Sun, Solubilization of carbon nanotubes via polymer attachment. Int. J. Nanosci. 1, 213–221 (2002)

    Article  CAS  Google Scholar 

  • C.Y. Hu, Y.J. Xu, S.W. Duo, R.F. Zhang, M.S. Li, Non-covalent functionalization of carbon nanotubes with surfactants and polymers. J. Chin. Chem. Soc. 56, 234–239 (2009)

    Article  CAS  Google Scholar 

  • W. Huang, Y. Lin, S. Taylor, J. Gaillard, A.M. Rao, Y.-P. Sun, Sonication-assisted functionalization and solubilization of carbon nanotubes. Nano Lett. 2, 231–234 (2002)

    Article  CAS  Google Scholar 

  • M. Ikeda, T. Hasegawa, M. Numata, K. Sugikawa, K. Sakurai, M. Fujiki, S. Shinkai, Instantaneous inclusion of a polynucleotide and hydrophobic guest molecules into a helical core of cationic β-1, 3-glucan polysaccharide. J. Am. Chem. Soc. 129, 3979–3988 (2007)

    Article  CAS  Google Scholar 

  • V.N. Khabashesku, Covalent functionalization of carbon nanotubes: synthesis, properties and applications of fluorinated derivatives. Russ. Chem. Rev. 80, 705 (2011)

    Article  CAS  Google Scholar 

  • O.-K. Kim, J. Je, J.W. Baldwin, S. Kooi, P.E. Pehrsson, L.J. Buckley, Solubilization of single-wall carbon nanotubes by supramolecular encapsulation of helical amylose. J. Am. Chem. Soc. 125, 4426–4427 (2003)

    Article  CAS  Google Scholar 

  • C.L. Lay, J. Liu, Y. Liu, Functionalized carbon nanotubes for anticancer drug delivery. Expert Rev. Med. Devices 8, 561–566 (2011)

    Article  CAS  Google Scholar 

  • J.U. Lee, J. Huh, K.H. Kim, C. Park, W.H. Jo, Aqueous suspension of carbon nanotubes via non-covalent functionalization with oligothiophene-terminated poly (ethylene glycol). Carbon 45, 1051–1057 (2007)

    Article  CAS  Google Scholar 

  • Y. Lin, D.E. Hill, J. Bentley, L.F. Allard, Y.-P. Sun, Characterization of functionalized single-walled carbon nanotubes at individual nanotube-thin bundle level. J. Phys. Chem. B 107, 10453–10457 (2003)

    Article  CAS  Google Scholar 

  • Y. Lin, A.M. Rao, B. Sadanadan, E.A. Kenik, Y.-P. Sun, Functionalizing multiple-walled carbon nanotubes with aminopolymers. J. Phys. Chem. B 106, 1294–1298 (2002)

    Article  CAS  Google Scholar 

  • L. Liu, T. Wang, J. Li, Z.-X. Guo, L. Dai, D. Zhang, D. Zhu, Self-assembly of gold nanoparticles to carbon nanotubes using a thiol-terminated pyrene as interlinker. Chem. Phys. Lett. 367, 747–752 (2003)

    Article  CAS  Google Scholar 

  • Z. Liu, S. Tabakman, K. Welsher, H. Dai, Carbon nanotubes in biology and medicine: in vitro and in vivo detection, imaging and drug delivery. Nano Res. 2, 85–120 (2009)

    Article  CAS  Google Scholar 

  • S. Mahajan, A. Patharkar, K. Kuche, R. Maheshwari, P.K. Deb, K. Kalia, R.K. Tekade, Functionalized carbon nanotubes as emerging delivery system for the treatment of cancer. Int. J. Pharm. 548, 540–558 (2018)

    Article  CAS  Google Scholar 

  • S. Niyogi, H. Hu, M. Hamon, P. Bhowmik, B. Zhao, S. Rozenzhak, J. Chen, M. Itkis, M. Meier, R. Haddon, Chromatographic purification of soluble single-walled carbon nanotubes (s-SWNTs). J. Am. Chem. Soc. 123, 733–734 (2001)

    Article  CAS  Google Scholar 

  • F. Pennetreau, C. Vriamont, B. Vanhorenbeke, O. Riant, S. Hermans, Covalent functionalization of carbon nanotubes with xanthates and peroxides. Eur. J. Org. Chem. 2015, 1804–1810 (2015)

    Article  CAS  Google Scholar 

  • X. Qi, W. Pinghua, S. Zhichun, Covalent functionalization of carbon nanotubes. Prog. Chem. -Beijing 19, 101 (2007)

    Google Scholar 

  • A. Star, J.F. Stoddart, Dispersion and solubilization of single-walled carbon nanotubes with a hyperbranched polymer. Macromolecules 35, 7516–7520 (2002)

    Article  CAS  Google Scholar 

  • Y.-P. Sun, W. Huang, Y. Lin, K. Fu, A. Kitaygorodskiy, L.A. Riddle, Y.J. Yu, D.L. Carroll, Soluble dendron-functionalized carbon nanotubes: preparation, characterization, and properties. Chem. Mater. 13, 2864–2869 (2001)

    Article  CAS  Google Scholar 

  • B.J. Taft, A.D. Lazareck, G.D. Withey, A. Yin, J. Xu, S.O. Kelley, Site-specific assembly of DNA and appended cargo on arrayed carbon nanotubes. J. Am. Chem. Soc. 126, 12750–12751 (2004)

    Article  CAS  Google Scholar 

  • H. Xin, A.T. Woolley, DNA-templated nanotube localization. J. Am. Chem. Soc. 125, 8710–8711 (2003)

    Article  CAS  Google Scholar 

  • L.Y. Yan, Y.F. Poon, M. Chan-Park, Y. Chen, Q. Zhang, Individually dispersing single-walled carbon nanotubes with novel neutral pH water-soluble chitosan derivatives. J. Phys. Chem. C 112, 7579–7587 (2008)

    Article  CAS  Google Scholar 

  • K. Zare, V.K. Gupta, O. Moradi, A.S.H. Makhlouf, M. Sillanpää, M.N. Nadagouda, H. Sadegh, R. Shahryari-Ghoshekandi, A. Pal, Z-j Wang, A comparative study on the basis of adsorption capacity between CNTs and activated carbon as adsorbents for removal of noxious synthetic dyes: a review. J. Nanostruct. Chem. 5, 227–236 (2015)

    Article  CAS  Google Scholar 

  • B. Zhao, H. Hu, S. Niyogi, M.E. Itkis, M.A. Hamon, P. Bhowmik, M.S. Meier, R.C. Haddon, Chromatographic purification and properties of soluble single-walled carbon nanotubes. J. Am. Chem. Soc. 123, 11673–11677 (2001)

    Article  CAS  Google Scholar 

  • S. Zhu, G. Xu, Single-walled carbon nanohorns and their applications. Nanoscale 2, 2538–2549 (2010)

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Pharmacy, Shri Venkateshwara University, Amroha, Uttar Pradesh, India

    Md Saquib Hasnain

  2. Department of Pharmaceutics, Seemanta Institute of Pharmaceutical Science, Mayurbhanj, Odisha, India

    Amit Kumar Nayak

Authors
  1. Md Saquib Hasnain
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  2. Amit Kumar Nayak
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Correspondence to Md Saquib Hasnain .

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Hasnain, M.S., Nayak, A.K. (2019). Functionalization of Carbon Nanotubes. In: Carbon Nanotubes for Targeted Drug Delivery. SpringerBriefs in Applied Sciences and Technology. Springer, Singapore. https://doi.org/10.1007/978-981-15-0910-0_4

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