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Pattern formation in the developing visual cortex: Topological defects, their generation, motion, and annihilation

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Statistical Mechanics of Biocomplexity

Part of the book series: Lecture Notes in Physics ((LNP,volume 527))

Abstract

The pinwheel-like arrangement of iso-orientation domains around orientation centers is a ubiquitous structural element of orientation preference maps in primary visual cortex. We show that activity-dependent self-organization of orientation preference implies that low densities of orientation centers develop through an initial overproduction and subsequent annihilation of pinwheels. Monitoring their density during development therefore offers a powerful novel approach to test whether orientation preference arises by activity-dependent mechanisms or is intrinsically predetermined. Observed interspecies differences in the density of orientation centers can be explained by a dynamic interaction of ocular dominance and orientation columns during development.

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  1. Max-Planck Institut für Strömungsforschung, Bunsenstrase 10, D-37073, Göttingen, Germany

    F. Wolf & T. Geisel

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  1. F. Wolf
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  2. T. Geisel
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D. Reguera J.M.G. Vilar J.M. Rubí

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© 1999 Springer-Verlag

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Wolf, F., Geisel, T. (1999). Pattern formation in the developing visual cortex: Topological defects, their generation, motion, and annihilation. In: Reguera, D., Vilar, J., Rubí, J. (eds) Statistical Mechanics of Biocomplexity. Lecture Notes in Physics, vol 527. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0105017

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  • DOI: https://doi.org/10.1007/BFb0105017

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  • Print ISBN: 978-3-540-66245-7

  • Online ISBN: 978-3-540-48486-8

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