Construction of Carbocycles via Zirconacycles and Titanacycles

Abstract

Metal-mediated selective construction of useful carbocyclic compounds from multi-component reaction systems has attracted much attention in recent years. Zirconocene (containing a Cp₂Zr unit) and titanocene (containing a Cp₂Ti unit) mediated reactions have made significant contributions to the development of synthetically useful methodologies for construction of carbocyclic compounds from different components. This review surveys applications of zirconacycles and titanacycles on construction of useful carbocyclic compounds from multi-components. A brief introduction into preparative methods for zirconacycles and titanacycles is also given.