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Advances in the Management of Cerebral Metastases

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Brain Tumors

Part of the book series: Contemporary Cancer Research ((CCR))

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Abstract

Brain metastases are the most common intracranial tumors in adults (23,48,62). Their incidence is thought to be increasing as a result of several factors, namely, early detection secondary to advances in diagnostic technology and prolonged survival from improved systemic chemotherapy.

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References

  1. Akslen L.A., Heuch I., Hartveit F. 1988. Metastatic patterns in autopsy cases of cutaneous melanoma. Invasion Metastasis 8:193–204.

    PubMed  CAS  Google Scholar 

  2. Alexander E. 3rd, Moriarty T.M., Davis R.B., Wen P.Y., Fine H.A., Black P.M., et al. 1995. Stereotactic radiosurgery for the definitive, noninvasive treatment of brain metastases. J. Natl. Cancer Inst. 87:34–40.

    PubMed  Google Scholar 

  3. Alexander E. 3rd, Moriarty T.M., Loeffler J.S. 1996. Radiosurgery for metastases. J. Neurooncol. 27:279–285.

    PubMed  Google Scholar 

  4. Amer M.H., Al-Sarraf M., Baker L.H., Vaitkevicius V.K. 1978. Malignant melanoma and central nervous system metastases: incidence, diagnosis, treatment and survival. Cancer 42:660–668.

    PubMed  CAS  Google Scholar 

  5. Auchter R.M., Lamond J.P., Alexander E., Buatti J.M., Chappell R., Friedman W.A., et al. 1996. A multiinstitutional outcome and prognostic factor analysis of radiosurgery for resectable single brain metastasis. Int. J. Radiat. Oncol. Biol. Phys. 35:27–35.

    PubMed  CAS  Google Scholar 

  6. Auperin A., Arriagada R., Pignon J.P., Le Pechoux C., Gregor A., Stephens R.J., et al. 1999. Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission. Prophylactic Cranial Irradiation Overview Collaborative Group. N. Engl. J. Med. 341:476–484.

    PubMed  CAS  Google Scholar 

  7. Aznavoorian S., Murphy A.N., Stetler-Stevenson W.G., Liotta L.A. 1993. Molecular aspects of tumor cell invasion and metastasis. Cancer 71:1368–1383.

    PubMed  CAS  Google Scholar 

  8. Batson O. 1941. The role of the vertebral veins in metastatic processes. Ann. Int. Med. 16: 38–45.

    Google Scholar 

  9. Berger M.S., Rostomily R.C. 1997. Low grade gliomas: functional mapping resection strategies, extent of resection, and outcome. J. Neurooncol. 34:85–101.

    PubMed  CAS  Google Scholar 

  10. Bindal A.K., Bindal R.K., Hess K.R., Shiu A., Hassenbusch S.J., Shi W.M., Sawaya R. 1996. Surgery versus radiosurgery in the treatment of brain metastasis. J. Neurosurg. 84:748–754.

    PubMed  CAS  Google Scholar 

  11. Bindal R.K., Bindal A.K., Sawaya R. 1997. Outcome of surgical therapy for metastatic cancer to the brain. Advances in Surgery 31:351–373.

    PubMed  CAS  Google Scholar 

  12. Bindal R.K., Sawaya R., Leavens M.E., Hess K.R., Taylor S.H. 1995. Reoperation for recurrent metastatic brain tumors. J. Neurosurg. 83:600–604.

    PubMed  CAS  Google Scholar 

  13. Bindal R.K., Sawaya R., Leavens M.E., Lee J.J. 1993. Surgical treatment of multiple brain metastases. J. Neurosurg. 79:210–216.

    PubMed  CAS  Google Scholar 

  14. Black P M., Moriarty T., Alexander E., Stieg P., Woodard E.J., Gleason P.L., et al. 1997. Development and implementation of intraoperative magnetic resonance imaging and its neurosurgical applications. Neurosurgery 41:831–842; discussion 842–845.

    PubMed  CAS  Google Scholar 

  15. Boldrey E., Sheline G. 1966. Delayed transitory clinical manifestations after radiation treatment of intracranial tumors. Acta. Radiol. Ther. Phys. Biol. 5:5–10.

    Google Scholar 

  16. Borgelt B., Gelber R., Kramer S., Brady L.W., Chang C.H., Davis L.W., et al. 1980. The palliation of brain metastases: final results of the first two studies by the Radiation Therapy Oncology Group. Int. J. Radiat. Oncol. Biol. Phys. 6:1–9.

    PubMed  CAS  Google Scholar 

  17. Breneman J.C., Warnick R.E., Albright R.E. Jr., Kukiatinant N., Shaw J., Armin D., Tew J. Jr. 1997. Stereotactic radiosurgery for the treatment of brain metastases. Results of a single institution series. Cancer 79:551–557.

    PubMed  CAS  Google Scholar 

  18. Burt M., Wronski M., Arbit E., Galicich J.H. 1992. Resection of brain metastases from non-small-cell lung carcinoma. Results of therapy. Memorial Sloan-Kettering Cancer Center Thoracic Surgical Staff. J. Thorac. Cardiovasc. Surg. 103:399–410; discussion 410-411.

    PubMed  CAS  Google Scholar 

  19. Cairncross J.G., Kim J.H., Posner J.B. 1980. Radiation therapy for brain metastases. Ann. Neurol. 7:529–541.

    PubMed  CAS  Google Scholar 

  20. Chason J., Walker F., Landers J. 1963. Metastatic carcinoma in the central nervous system and dorsal root ganglia. A prospective autopsy study. Cancer 16:781–787.

    PubMed  CAS  Google Scholar 

  21. Coffey R.J., Flickinger J.C., Bissonette D.J., Lunsford L.D. 1991. Radiosurgery for solitary brain metastases using the cobalt-60 gamma unit: methods and results in 24 patients. Int. J. Radiat. Oncol. Biol. Phys. 20:1287–1295.

    PubMed  CAS  Google Scholar 

  22. Cox J.D., Stanley K., Petrovich Z., Paig C., Yesner R. 1981. Cranial irradiation in cancer of the lung of all cell types. Jama 245:469–472.

    PubMed  CAS  Google Scholar 

  23. Crowley M.J., O’Brien D.F. 1993. Epidemiology of tumours of the central nervous system in Ireland. Ir. Med. J. 86: 87–88.

    PubMed  CAS  Google Scholar 

  24. DeAngelis LM. 1994. Management of brain metastases. Cancer Invest. 12:156–165.

    PubMed  CAS  Google Scholar 

  25. DeAngelis L.M., Delattre J.Y., Posner J.B. 1989. Radiation-induced dementia in patients cured of brain metastases. Neurology 39:789–796.

    PubMed  CAS  Google Scholar 

  26. DeAngelis L.M., Mandell L.R., Thaler H.T., Kimmel D.W., Galicich J.H., Fuks Z., Posner J.B. 1989. The role of postoperative radiotherapy after resection of single brain metastases. Neurosurgery 24: 798–805.

    PubMed  CAS  Google Scholar 

  27. Delattre J.Y., Krol G., Thaler H.T., Posner J.B. 1988. Distribution of brain metastases. Arch. Neurol. 45:741–744.

    PubMed  CAS  Google Scholar 

  28. Dosoretz D.E., Blitzer P.H., Russell A.H., Wang C.C. 1980. Management of solitary metastasis to the brain: the role of elective brain irradiation following complete surgical resection. Int. J. Radiat. Oncol. Biol. Phys. 6:1727–1730.

    PubMed  CAS  Google Scholar 

  29. Einhorn L.H., 3rd. 1995. The case against prophylactic cranial irradiation in limited small cell lung cancer. Semin. Radiat. Oncol. 5:57–60.

    PubMed  Google Scholar 

  30. Ewing E. 1928. Neoplastic Diseases, 6th ed. W.B. Saunders Co, Philadelphia, PA.

    Google Scholar 

  31. Fidler I.J. 2000. Angiogenesis and cancer metastasis. Cancer J. Sci. Am. 6(Suppl 2): S134–S141.

    Google Scholar 

  32. Fidler I.J. 1991. Cancer metastasis. Br. Med. Bull. 47:157–177.

    PubMed  CAS  Google Scholar 

  33. Fidler I.J. 1990. Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture. Cancer Res. 50:6130–6138.

    PubMed  CAS  Google Scholar 

  34. Fidler I.J. 1990. Host and tumour factors in cancer metastasis. Eur. J. Clin. Invest. 20: 481–486.

    PubMed  CAS  Google Scholar 

  35. Fidler I.J. 1995. Modulation of the organ microenvironment for treatment of cancer metastasis. J. Natl. Cancer Inst. 87: 1588–1592.

    PubMed  CAS  Google Scholar 

  36. Fidler I.J. 1997. Molecular biology of cancer: invasion and metastasis, in Cancer: Principles and Practice of Oncology (DeVita V.T, Hellman S., Rosenberg S.A., eds.), Lippincott-Raven, Philadelphia, PA, pp. 135–152.

    Google Scholar 

  37. Fidler I.J. 1991. Orthotopic implantation of human colon carcinomas into nude mice provides a valuable model for the biology and therapy of metastasis. Cancer Metastasis Rev. 10:229–243.

    PubMed  CAS  Google Scholar 

  38. Fidler I.J., Hart I.R. 1982. Biological diversity in metastatic neoplasms: origins and implications. Science 217:998–1003.

    PubMed  CAS  Google Scholar 

  39. Fidler I.J., Kripke M.L. 1977. Metastasis results from preexisting variant cells within a malignant tumor. Science 197: 893–895.

    PubMed  CAS  Google Scholar 

  40. Fidler I.J., Talmadge J.E. 1986. Evidence that intravenously derived murine pulmonary melanoma metastases can originate from the expansion of a single tumor cell. Cancer Res. 46:5167–5171.

    PubMed  CAS  Google Scholar 

  41. Flickinger J.C., Kondziolka D., Lunsford L.D., Coffey R.J., Goodman M.L., Shaw E.G., et al. 1994. A multi-institutional experience with stereotactic radiosurgery for solitary brain metastasis. Int. J. Radiat. Oncol. Biol. Phys. 28:797–802.

    PubMed  CAS  Google Scholar 

  42. Franzini A., Leocata F., Giorgi C., Allegranza A., Servello D., Broggi G. 1994. Role of stereotactic biopsy in multifocal brain lesions: considerations on 100 consecutive cases. J. Neurol. Neurosurg. Psychiatry 57:957–960.

    PubMed  CAS  Google Scholar 

  43. Fuller B.G., Kaplan I.D., Adler J., Cox R.S., Bagshaw M.A. 1992. Stereotaxic radiosurgery for brain metastases: the importance of adjuvant whole brain irradiation. Int. J. Radiat. Oncol. Biol. Phys. 23: 413–418.

    PubMed  CAS  Google Scholar 

  44. Galicich J.H., Sundaresan N., Arbit E., Passe S. 1980. Surgical treatment of single brain metastasis: factors associated with survival. Cancer 45:381–386.

    PubMed  CAS  Google Scholar 

  45. Gaspar, L., C. Scott, M. Rotman, S. Asbell, T. Phillips, T. Wasserman, et al. 1997. Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials. Int. J. Radiat. Oncol. Biol. Phys. 37:745–751.

    PubMed  CAS  Google Scholar 

  46. Graf A.H., Buchberger W., Langmayr H., Schmid K.W. 1988. Site preference of metastatic tumours of the brain. Virchows Arch. A. Pathol. Anat. Histopathol. 412:493–498.

    PubMed  CAS  Google Scholar 

  47. Grant F. 1926. Concerning intracranial malignant metastases. Their frequency and the value of surgery in their treatment. Ann. Surg. 84:635.

    PubMed  CAS  Google Scholar 

  48. Grant R., Whittle I.R., Collie D.A., Gregor A., Ironside J.W. 1996. Referral pattern and management of patients with malignant brain tumours in south east Scotland. Health Bull. (Edinb) 54:212–222.

    CAS  Google Scholar 

  49. Gregor A., Cull A., Stephens R.J., Kirkpatrick J.A., Yarnold J.R., Girling D.J., et al. 1997. Prophylactic cranial irradiation is indicated following complete response to induction therapy in small cell lung cancer: results of a multicentre randomised trial. United Kingdom Coordinating Committee for Cancer Research (UKCCCR) and the European Organization for Research and Treatment of Cancer (EORTC). Eur. J. Cancer 33:1752–1758.

    PubMed  CAS  Google Scholar 

  50. Haar F., Patterson R.H. Jr. 1972. Surgical for metastatic intracranial neoplasm. Cancer 30:1241–1245.

    PubMed  CAS  Google Scholar 

  51. Hammoud M.A., Ligon B.L., elSouki R., Shi W.M., Schomer D.F., Sawaya R. 1996. Use of intraoperative ultrasound for localizing tumors and determining the extent of resection: a comparative study with magnetic resonance imaging. J. Neurosurg. 84:737–741.

    PubMed  CAS  Google Scholar 

  52. Hansen H.H., Dombernowsky P., Hirsch F.R., Hansen M., Rygard J. 1980. Prophylactic irradiation in bronchogenic small cell anaplastic carcinoma. A comparative trial of localized versus extensive radiotherapy including prophylactic brain irradiation in patients receiving combination chemotherapy. Cancer 46:279–284.

    PubMed  CAS  Google Scholar 

  53. Hu F.N., Wang R.Y., Hsu T.C. 1987. Clonal origin of metastasis in B16 murine melanoma: a cytogenetic study. J. Natl. Cancer Inst. 78:155–163.

    PubMed  CAS  Google Scholar 

  54. Jackson D.V. Jr., Richards F. 2nd, Cooper M.R., Ferree C., Muss H.B., White D.R., Spurr C.L. 1977. Prophylactic cranial irradiation in small cell carcinoma of the lung. A randomized study. Jama 237: 2730–2733.

    PubMed  Google Scholar 

  55. Johnson J.D., Young B. 1996. Demographics of brain metastasis. Neurosurg. Clin. N. Am. 7: 337–344.

    PubMed  CAS  Google Scholar 

  56. Kehrli P. 1999. Epidemiology of brain metastases. Neurochirurgie 45:357–363.

    PubMed  CAS  Google Scholar 

  57. Kihlstrom L., Karlsson B., Lindquist C. 1993. Gamma Knife surgery for cerebral metastases. Implications for survival based on 16 years experience. Stereotact. Funct. Neurosurg. 61:45–50.

    PubMed  Google Scholar 

  58. Kondziolka D., Patel A., Lunsford L.D., Kassam A., Flickinger J.C. 1999. Stereotactic radiosurgery plus whole brain radiotherapy versus radiotherapy alone for patients with multiple brain metastases. Int. J. Radiat. Oncol. Biol. Phys. 45:427–434.

    PubMed  CAS  Google Scholar 

  59. Kurtz J.M., Gelber R., Brady L.W., Carella R.J., Cooper J.S.. 1981. The palliation of brain metastases in a favorable patient population: a randomized clinical trial by the Radiation Therapy Oncology Group. Int. J. Radiat. Oncol. Biol. Phys. 7:891–895.

    PubMed  CAS  Google Scholar 

  60. Lang F.F., Sawaya R. 1996. Surgical management of cerebral metastases. Neurosurg. Clin. N. Am. 7:459–484.

    PubMed  CAS  Google Scholar 

  61. Lang F.F., Sawaya R. 1998. Surgical treatment of metastatic brain tumors. Semin. Surg. Oncol. 14:53–63.

    PubMed  CAS  Google Scholar 

  62. Lassouw G.M., Twijnstra S., Schouten L.J., van de Pol M. 1992. The Neuro-Oncology Register. Neuroepidemiology 11:261–266.

    PubMed  CAS  Google Scholar 

  63. Littman P., Rosenstock J., Gale G., Krisch R.E., Meadows A., Sather H., et al. 1984. The somnolence syndrome in leukemic children following reduced daily dose fractions of cranial radiation. Int. J. Radiat. Oncol. Biol. Phys. 10:1851–1853.

    PubMed  CAS  Google Scholar 

  64. Loeffler J.S., Alexander E. 1993. Radiosurgery for the treatment of intracranial metastases, in Stereotactic Radiosurgery (Alexander E., Loeffler J.S., Lunsford L.D., eds.), McGraw-Hill, New York, pp. 197–206.

    Google Scholar 

  65. Markesbery W.R., Brooks W.H., Gupta G.D., Young A.B. 1978. Treatment for patients with cerebral metastases. Arch. Neurol. 35:754–756.

    PubMed  CAS  Google Scholar 

  66. Mehta M.P., Rozental J.M., Levin A.B., Mackie T.R., Kubsad S.S., Gehring M.A., Kinsella T.J. 1992. Defining the role of radiosurgery in the management of brain metastases. Int. J. Radiat. Oncol. Biol. Phys. 24:619–625.

    PubMed  CAS  Google Scholar 

  67. Merchut M.P. 1989. Brain metastases from undiagnosed systemic neoplasms. Arch. Intern. Med. 149:1076–1080.

    PubMed  CAS  Google Scholar 

  68. Mintz A.H., Kestle J., Rathbone M.P., Gaspar L., Hugenholtz H., Fisher B., et al. 1996. A randomized trial to assess the efficacy of surgery in addition to radiotherapy in patients with a single cerebral metastasis. Cancer 78:1470–1476.

    PubMed  CAS  Google Scholar 

  69. Noordijk E.M., Vecht C.J., Haaxma-Reiche H., Padberg G.W., Voormolen J.H., Hoekstra F.H., et al. 1994. The choice of treatment of single brain metastasis should be based on extracranial tumor activity and age. Int. J. Radiat. Oncol. Biol. Phys. 29:711–717.

    PubMed  CAS  Google Scholar 

  70. Oneschuk D., Bruera E. 1998. Palliative management of brain metastases. Support Care Cancer 6:365–372.

    PubMed  CAS  Google Scholar 

  71. Order S.E., Hellman S., Von Essen C.F., Kligerman M.M. 1968. Improvement in quality of survival following wholebrain irradiation for brain metastasis. Radiology 91:149–153.

    PubMed  CAS  Google Scholar 

  72. Paget S. 1989. The distribution of secondary growths in cancer of the breast. 1889. Cancer Metastasis Rev. 8:98–101.

    PubMed  CAS  Google Scholar 

  73. Patchell R. A. 1991. Brain metastases. Neurol. Clin. 9:817–824.

    PubMed  CAS  Google Scholar 

  74. Patchell R.A., Tibbs P.A., Regine W.F., Dempsey R.J., Mohiuddin M., Kryscio R.J., et al. 1998. Postoperative radiotherapy in the treatment of single metastases to the brain: a randomized trial. Jama 280:1485–1489.

    PubMed  CAS  Google Scholar 

  75. Patchell R.A., Tibbs P.A., Walsh J.W., Dempsey R.J., Maruyama Y., Kryscio R.J., et al. 1990. A randomized trial of surgery in the treatment of single metastases to the brain. N. Engl. J. Med. 322:494–500.

    PubMed  CAS  Google Scholar 

  76. Pavy J.J., Denekamp J., Letschert J., Littbrand B., Mornex F., Bernier J., et al. 1995. EORTC Late Effects Working Group. Late effects toxicity scoring: the SOMA scale. Radiother. Oncol. 35:11–15.

    PubMed  CAS  Google Scholar 

  77. Petrovich Z., Luxton G., Formenti S., Jozsef G., Zee C.S., Apuzzo M.L. 1996. Stereotactic radiosurgery for primary and metastatic brain tumors. Cancer Invest 14:445–454.

    PubMed  CAS  Google Scholar 

  78. Posner J.B. 1977. Management of central nervous system metastases. Semin. Oncol. 4:81–91.

    PubMed  CAS  Google Scholar 

  79. Posner J.B., Chernik N.L. 1978. Intracranial metastases from systemic cancer. Adv. Neurol. 19:579–592.

    PubMed  CAS  Google Scholar 

  80. Ransohoff J. 1975. Surgical management of metastatic tumors. Semin. Oncol. 2:21–27.

    PubMed  CAS  Google Scholar 

  81. Rubin P., Constine L.S. 3rd, Fajardo L.F., Phillips T.L., Wasserman T.H. 1995. EORTC Late Effects Working Group. Overview of late effects normal tissues (LENT) scoring system. Radiother. Oncol. 35: 9–10.

    PubMed  CAS  Google Scholar 

  82. Ruderman N., Hall T. 1965. Use of glucocorticoids in the palliative treatment of metastatic brain tumors. Cancer 18: 298–306.

    PubMed  CAS  Google Scholar 

  83. Russell A.H., Pajak T.E., Selim H.M., Paradelo J.C., Murray K., Bansal P., et al. 1991. Prophylactic cranial irradiation for lung cancer patients at high risk for development of cerebral metastasis: results of a prospective randomized trial conducted by the Radiation Therapy Oncology Group. Int. J. Radiat. Oncol. Biol. Phys. 21: 637–643.

    PubMed  CAS  Google Scholar 

  84. Rutigliano M.J., Lunsford L.D., Kondziolka D., Strauss M.J., Khanna V., Green M. 1995. The cost effectiveness of stereotactic radiosurgery versus surgical resection in the treatment of solitary metastatic brain tumors. Neurosurgery 37:445–453; discussion 453-455.

    PubMed  CAS  Google Scholar 

  85. Salvati M., Cervoni L., Raco A. 1995. Single brain metastases from unknown primary malignancies in CT-era. J. Neurooncol. 23:75–80.

    PubMed  CAS  Google Scholar 

  86. Sause W.T., Crowley J.J., Morantz R., Rotman M., Mowry P.A., Bouzaglou A., et al. 1990. Solitary brain metastasis: results of an RTOG/SWOG protocol evaluation surgery + RT versus RT alone. Am. J. Clin. Oncol. 13:427–432.

    PubMed  CAS  Google Scholar 

  87. Schaefer P.W., Budzik R.F. Jr., Gonzalez R.G. 1996. Imaging of cerebral metastases. Neurosurg. Clin. N. Am. 7:393–423.

    PubMed  CAS  Google Scholar 

  88. Schöggl A., Kitz K., Reddy M., Wolfsberger S., Schneider B., Dieckmann K., Ungersbock K. 2000. Defining the role of stereotactic radiosurgery versus microsurgery in the treatment of single brain metastases. Acta. Neurochir. 142:621–626.

    Google Scholar 

  89. Shah S.H., Soomro I.N., Hussainy A.S., Hassan S.H. 1999. Clinico-morphological pattern of intracranial tumors in children. J. Pak. Med. Assoc. 49:63–65.

    PubMed  CAS  Google Scholar 

  90. Simonova G., Liscak R., Novotny J. Jr., Novotny J. 2000. Solitary brain metastases treated with the Leksell gamma knife: prognostic factors for patients. Radiother. Oncol. 57:207–213.

    PubMed  CAS  Google Scholar 

  91. Skibber J.M., Soong S.J., Austin L., Balch C.M., Sawaya R.E. 1996. Cranial irradiation after surgical excision of brain metastases in melanoma patients. Ann. Surg. Oncol. 3:118–123.

    PubMed  CAS  Google Scholar 

  92. Smalley S.R., Schray M.F., Laws E.R., O’Fallon J.R. 1987. Adjuvant radiation therapy after surgical resection of solitary brain metastasis: association with pattern of failure and survival. Int. J. Radiat. Oncol. Biol. Phys. 13:1611–1616.

    PubMed  CAS  Google Scholar 

  93. Sneed P.K., Lamborn K.R., Forstner J.M., McDermott M.W., Chang S., Park E., et al. 1999. Radiosurgery for brain metastases: is whole brain radiotherapy necessary? Int. J. Radiat. Oncol. Biol. Phys. 43: 549–558.

    PubMed  CAS  Google Scholar 

  94. Sneed P.K., Larson D.A., Wara W.M. 1996. Radiotherapy for cerebral metastases. Neurosurg. Clin. N. Am. 7:505–515.

    PubMed  CAS  Google Scholar 

  95. Sperduto P.W., Hall W.A. 1996. Radiosurgery, cost-effectiveness, gold standards, the scientific method, cavalier cowboys, and the cost of hope. Int. J. Radiat. Oncol. Biol. Phys. 36:511–513.

    PubMed  CAS  Google Scholar 

  96. Sturm V., Kimmig B., Engenhardt R., Schlegel W., Pastyr O., Treuer H., et al. 1991. Radiosurgical treatment of cerebral metastases. Method, indications and results. Stereotact. Funct. Neurosurg. 57: 7–10.

    PubMed  CAS  Google Scholar 

  97. Sugarbaker E.V. 1979. Cancer Metastasis: a product of tumor-host interactions. Curr. Prob. Cancer 3:1–59.

    CAS  Google Scholar 

  98. Talmadge J.E., Wolman S.R., Fidler I.J. 1982. Evidence for the clonal origin of spontaneous metastases. Science 217: 361–363.

    PubMed  CAS  Google Scholar 

  99. Vecht C.J. 1998. Clinical management of brain metastasis. J. Neurol. 245:127–131.

    PubMed  CAS  Google Scholar 

  100. Vecht C.J., Haaxma-Reiche H., Noordijk E.M., Padberg G.W., Voormolen J.H., Hoekstra F.H., et al. 1993. Treatment of single brain metastasis: radiotherapy alone or combined with neurosurgery? Ann. Neurol. 33:583–590.

    PubMed  CAS  Google Scholar 

  101. Vermeulen S.S. 1998. Whole brain radiotherapy in the treatment of metastatic brain tumors. Sem. Surg. Oncol. 14:64–69.

    CAS  Google Scholar 

  102. Vives K.P., Piepmeier J.M. 1999. Complications and expected outcome of glioma surgery. J. Neurooncol. 42:289–302.

    PubMed  CAS  Google Scholar 

  103. Voorhies R.M., Sundaresan N., Thaler H.T. 1980. The single supratentorial lesion. An evaluation of preoperative diagnostic tests. J. Neurosurg. 53:364–368.

    PubMed  CAS  Google Scholar 

  104. White K.T., Fleming T.R., Laws E.R. 1981. Single metastasis to the brain. Surgical treatment in 122 consecutive patients. Mayo Clin. Proc. 56:424–428.

    PubMed  CAS  Google Scholar 

  105. Winston K.R., Walsh J.W., Fischer E.G. 1980. Results of operative treatment of intracranial metastatic tumors. Cancer 45:2639–2645.

    PubMed  CAS  Google Scholar 

  106. Wronski M., Arbit E., Burt M., Galicich J.H. 1995. Survival after surgical treatment of brain metastases from lung cancer: a follow-up study of 231 patients treated between 1976 and 1991. J. Neurosurg. 83: 605–616.

    PubMed  CAS  Google Scholar 

  107. Young R.F. 1998. Radiosurgery for the treatment of brain metastases. Semin. Surg. Oncol. 14:70–78.

    PubMed  CAS  Google Scholar 

  108. Zakhary R., Keles G.E., Berger M.S. 1999. Intraoperative imaging techniques in the treatment of brain tumors. Curr. Opin. Oncol. 11:152–156.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Neurosurgery, The University of Texas M. D. Anderson Cancer Center, Houston, TX

    Fadi Hanbali MD & Raymond Sawaya MD

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  1. Fadi Hanbali MD
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  2. Raymond Sawaya MD
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Editors and Affiliations

  1. Department of Surgery, Duke University Medical Center, Durham, NC

    Francis Ali-Osman DSc

  2. Comprehensive Cancer Center, Duke University Medical Center, Durham, NC

    Francis Ali-Osman DSc

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Hanbali, F., Sawaya, R. (2005). Advances in the Management of Cerebral Metastases. In: Ali-Osman, F. (eds) Brain Tumors. Contemporary Cancer Research. Humana Press. https://doi.org/10.1385/1-59259-843-9:307

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