1. Optimizing interstitial delivery of BCNU from controlled release polymers for the treatment of brain tumors

   • Eric P. Sipos
   • Betty Tyler
   • H. Brem

   ORIGINAL ARTICLE Pages: 383 - 389

2. Antiestrogenic activity of DP-TAT-59, an active metabolite of TAT-59 against human breast cancer

   • T. Toko
   • Jiro Shibata
   • Yuji Yamada

   ORIGINAL ARTICLE Pages: 390 - 398

3. Potentiation of etoposide-induced apoptosis by staurosporine in human tumor cells is associated with events downstream of DNA-protein complex formation

   • Richard B. Lock
   • Bruce S. Thompson
   • Lolita Stribinskiene

   ORIGINAL ARTICLE Pages: 399 - 409

4. Preclinical trial of doxorubicin entrapped in sterically stabilized liposomes in dogs with spontaneously arising malignant tumors

   • D. M. Vail
   • Laura D. Kravis
   • E. Gregory MacEwen

   ORIGINAL PAPER Pages: 410 - 416

5. Induction of apoptosis in multi-drug resistant (MDR) human glioblastoma cells by SN-38, a metabolite of the camptothecin derivative CPT-11

   • Shouji Nakatsu
   • S. Kondo
   • Gene H. Barnett

   ORIGINAL ARTICLE Pages: 417 - 423

6. The potential of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide]to circumvent three multidrug-resistance phenotypes in vitro

   • R. A. Davey
   • Gloria M. Su
   • Mary W. Davey

   ORIGINAL ARTICLE Pages: 424 - 430

7. Urinary excretion of ifosfamide, 4-hydroxyifosfamide, 3- and 2-dechloroethylifosfamide, mesna, and dimesna in patients on fractionated intravenous ifosfamide and concomitant mesna therapy

   • V. Kurowski
   • T. Wagner

   ORIGINAL ARTICLE Pages: 431 - 439

8. Modulation of glucuronidation of SN-38, the active metabolite of irinotecan, by valproic acid and phenobarbital

   • E. Gupta
   • Xiaolin Wang
   • M. J. Ratain

   ORIGINAL ARTICLE Pages: 440 - 444

9. Ras oncogene-transformed and nontransformed cell populations are each heterogeneous but respond differently to the chemotherapeutic drug cytosine arabinoside (Ara-C)

   • D. E. Axelrod
   • Y. Gusev
   • John W. Gamel

   ORIGINAL ARTICLE Pages: 445 - 451

10. Superiority of cyclosporin A over PSC-833 in enhancement of VP-16 efficacy in murine tumors in vivo

    • L. M. Slater
    • Paula Sweet
    • Kathyrn Osann

    ORIGINAL ARTICLE Pages: 452 - 454

11. DNA topoisomerase II-dependent cytotoxicity of alkylaminoanthraquinones and their N-oxides

    • P. J. Smith
    • Nicola J. Blunt
    • Laurence H. Patterson

    ORIGINAL ARTICLE Pages: 455 - 461

12. Incidence of objectively diagnosed thromboembolic disease in cancer patients undergoing cytotoxic chemotherapy and / or hormonal therapy

    • A. A. Shlebak
    • D. B. Smith

    SHORT COMMUNICATION Pages: 462 - 466

13. Differential toxicity of camptothecin, topotecan and 9-aminocamptothecin to human, canine, and murine myeloid progenitors (CFU-GM) in vitro

    • C. L. Erickson-Miller
    • Richard D. May
    • Ralph E. Parchment

    SHORT COMMUNICATION Pages: 467 - 472