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Fmoc Solid-Phase Peptide Synthesis

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Peptide Antibodies

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1348))

Abstract

Synthetic peptides are important as drugs and in research. Currently, the method of choice for producing these compounds is solid-phase peptide synthesis. In this nonspecialist review, we describe the scope and limitations of Fmoc solid-phase peptide synthesis. Furthermore, we provide a detailed protocol for Fmoc peptide synthesis.

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Authors and Affiliations

  1. Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

    Paul R. Hansen & Alberto Oddo

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  1. Paul R. Hansen
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  2. Alberto Oddo
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Correspondence to Paul R. Hansen .

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Editors and Affiliations

  1. Statens Serum Institut, Copenhagen, Denmark

    Gunnar Houen

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Hansen, P.R., Oddo, A. (2015). Fmoc Solid-Phase Peptide Synthesis. In: Houen, G. (eds) Peptide Antibodies. Methods in Molecular Biology, vol 1348. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2999-3_5

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  • DOI: https://doi.org/10.1007/978-1-4939-2999-3_5

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-2998-6

  • Online ISBN: 978-1-4939-2999-3

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