Abstract
Distillation-precipitation polymerization of divinylbenzene was applied to obtain uniform-sized polymeric microspheres. The microspheres were then modified with polypentafluorostyrene chains utilizing surface-initiated atom transfer radical polymerization techniques. The hydrophobic fluoropolymer-coated microsphere was then converted to a hydrophilic biopolymer by performing thiol-halogen click chemistry between polypentafluorostyrene and 1-thio-β-d-glucose sodium salt. The semi-fluorinated glycopolymer showed good binding ability with Concanavalin A as determined by confocal microscopy and turbidity experiments.
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Acknowledgments
The authors are grateful for financial support from the Australian Research Council (ARC) in the form of a Discovery Grant (DP0877122).
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Song, W., Granville, A.M. (2016). Surface Modification of Polydivinylbenzene Microspheres with a Fluorinated Glycopolymer Using Thiol-Halogen Click Chemistry. In: Sun, XL. (eds) Macro-Glycoligands. Methods in Molecular Biology, vol 1367. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-3130-9_10
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DOI: https://doi.org/10.1007/978-1-4939-3130-9_10
Publisher Name: Humana Press, New York, NY
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Online ISBN: 978-1-4939-3130-9
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