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Functional MRI: Applications in Cognitive Neuroscience

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fMRI Techniques and Protocols

Part of the book series: Neuromethods ((NM,volume 119))

Abstract

Neuroimaging, in many respects, revolutionized the study of cognitive neuroscience, the discipline that attempts to determine the neural mechanisms underlying cognitive processes. Early studies of brain–behavior relationships relied on a precise neurological exam as the basis for hypothesizing the site of brain damage that was responsible for a given behavioral syndrome. The advent of structural brain imaging, first with computerized tomography and later with magnetic resonance imaging, paved the way for more precise anatomical localization of the cognitive deficits that manifest after brain injury. Functional neuroimaging, broadly defined as techniques that provide measures of brain activity, further increased our ability to study the neural basis of behavior. Functional MRI (fMRI), in particular, is an extremely powerful technique that affords excellent spatial and temporal resolution. This chapter focuses on the principles underlying fMRI as a cognitive neuroscience tool for exploring brain–behavior relationships.

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Authors and Affiliations

  1. Helen Wills Neuroscience Institute, University of California, 132 Barker Hall, Berkeley, CA, 94720-1650, USA

    Mark D’Esposito M.D.

  2. Department of Neurology, UCSF, San Francisco, CA, USA

    Andrew Kayser

  3. Department of Neurology, Northern California VA Health Care System, 132 Barker Hall, Martinez, CA, USA

    Anthony Chen

Authors
  1. Mark D’Esposito M.D.
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  2. Andrew Kayser
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  3. Anthony Chen
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Corresponding author

Correspondence to Mark D’Esposito M.D. .

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Editors and Affiliations

  1. Neuroimaging Research Unit, INSPE, Division of Neuroscience, San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy

    Massimo Filippi

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D’Esposito, M., Kayser, A., Chen, A. (2016). Functional MRI: Applications in Cognitive Neuroscience. In: Filippi, M. (eds) fMRI Techniques and Protocols. Neuromethods, vol 119. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-5611-1_11

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  • DOI: https://doi.org/10.1007/978-1-4939-5611-1_11

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