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Identification of Long Noncoding RNAs Associated to Human Disease Susceptibility

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Promoter Associated RNA

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1543))

Abstract

Transcriptomic as well as in vivo studies have revealed the importance of several lncRNAs in many complex diseases including cancer, cardiovascular, and neurological disorders. In this protocol, we describe how to perform RNAseq data analysis to identify lncRNAs associated with disease states utilizing the open-source software CANEapp (application for Comprehensive automated Analysis of Next-generation sequencing Experiments).

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Author information

Authors and Affiliations

  1. Center for Therapeutic Innovation, Department of Psychiatry and Behavioral Sciences, University of Miami, Miller School of Medicine, 1501 NW 10th Ave., Miami, 33136, FL, USA

    Marco Magistri

  2. Department of Psychiatry and Behavioral Sciences, Center for Therapeutic Innovation, Miller School of Medicine, University of Miami, 1501 NW 10th Ave., Miami, FL, 33136, USA

    Dmitry Velmeshev

Authors
  1. Marco Magistri
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  2. Dmitry Velmeshev
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Corresponding author

Correspondence to Marco Magistri .

Editor information

Editors and Affiliations

  1. Experimental Therapeutics Group, Institute of Oncology Research, Bellinzona, Switzerland

    Sara Napoli

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Magistri, M., Velmeshev, D. (2017). Identification of Long Noncoding RNAs Associated to Human Disease Susceptibility. In: Napoli, S. (eds) Promoter Associated RNA. Methods in Molecular Biology, vol 1543. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6716-2_10

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  • DOI: https://doi.org/10.1007/978-1-4939-6716-2_10

  • Published:

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-6714-8

  • Online ISBN: 978-1-4939-6716-2

  • eBook Packages: Springer Protocols

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