Abstract
Kinetochores are essential for the proper positioning, movement and segregation of chromosomes on spindle microtubules. Live cell analyses of kinetochore movements on the spindle provide an important tool for dissecting the molecular machinery underlying kinetochore-based chromosome motility. Here, we describe contemporary techniques for studying and manipulating kinetochore function in live Drosophila syncytial blastoderm-stage embryos and S2 cells.
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Buster, D.W., Sharp, D.J. (2007). Live Cell Approaches for Studying Kinetochore-Microtubule Interactions in Drosophila. In: Zhou, J. (eds) Microtubule Protocols. Methods in Molecular Medicine™, vol 137. Humana Press. https://doi.org/10.1007/978-1-59745-442-1_10
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DOI: https://doi.org/10.1007/978-1-59745-442-1_10
Publisher Name: Humana Press
Print ISBN: 978-1-58829-642-9
Online ISBN: 978-1-59745-442-1
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