Skip to main content

Organic Acids by Ion Chromatography

  • Protocol
Liquid Chromatography In Clinical Analysis

Part of the book series: Biological Methods ((BM))

Abstract

The presence of increased levels of various organic acids in physiological fluids such as serum, plasma, and urine has been correlated with a variety of diseases (1). Although some are rare, others such as lactic acidosis and hyperoxaluria are more widespread (2, 3). The estimation of organic acids in biological fluids has long been an analytical problem owing to the nature of the samples and the hydrophilic behavior of the various acids.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Protocol
USD 49.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Snyder, L. R., Karger, B. L., and Giese, R. W., Contemp. Top. Anal. Clin. Chem. 2, 230 (1978).

    Google Scholar 

  2. Chalmers, R. A., Lawson, A. M., and Borud, D., Clin. Chem. Acta 77, 117 (1977).

    Article  CAS  Google Scholar 

  3. Charransol, G., Barthelemy, C., and Peagrey, P., J. Chromatogr. 145, 452 (1978).

    CAS  Google Scholar 

  4. Goodman, S. I., Helland, P., Stokke, O., and Jellum, E., J. Chromatogr. 141, 497 (1977).

    Google Scholar 

  5. Molnar, I., and Horvath, C., J. Chromatogr. 143, 391 (1977).

    CAS  Google Scholar 

  6. Miyagi, H., Miura, J., Takata, Y., and Canno, S., Clin. Chem. 25, 1617 (1979).

    CAS  Google Scholar 

  7. Small, H., Stevens, T., and Bauman, W., Anal. Chem. 47, 1801 (1975).

    Article  CAS  Google Scholar 

  8. Wheaton, R. W., and Bauman, W. C., Ind. Eng. Chem. 45, 228 (1953).

    Article  CAS  Google Scholar 

  9. Turkelson, V. T., and Richards, M., Anal. Chem. 50, 1420 (1978).

    Article  CAS  Google Scholar 

  10. Rich, W., Smith, F., McNeill, L., and Sidebottom, T., Ion Exclusion Coupled to Ion Chromatography: Instrumentation and Application, in Ion Chromatographic Analysis of Environmental Pollutants, Vol. 2, Ann Arbor Science Press, Ann Arbor, Michigan, 1979, p. 17.

    Google Scholar 

  11. Wittmann, P., Haslbeck, M., Bachmann, W., and Mehnert, M., Deutsch. Med. Wochenschr. 102, 5 (1977).

    Article  CAS  Google Scholar 

  12. Afifi, A. A., Chang, P. C., Lin, V. Y., et al, Am. J. Cardiol. 33, 826 (1974).

    Article  CAS  Google Scholar 

  13. Laurence, D. R., Clinical Pharmacology, 4th ed., Churchill Livingstone, Edinburgh, 1973, p. 284

    Google Scholar 

  14. Sundaram, P. V., and Hinsch, W., Clin. Chem. 25, 285 (1979).

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1981 The Humana Press, Inc.

About this protocol

Cite this protocol

Rich, W.E., Johnson, E., Lois, L., Stafford, B.E., Kabra, P.M., Marton, L.J. (1981). Organic Acids by Ion Chromatography. In: Kabra, P.M., Marton, L.J. (eds) Liquid Chromatography In Clinical Analysis. Biological Methods. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60327-404-3_17

Download citation

  • DOI: https://doi.org/10.1007/978-1-60327-404-3_17

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-0-89603-026-8

  • Online ISBN: 978-1-60327-404-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics