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Microfluidics in Protein Chromatography

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Protein Chromatography

Part of the book series: Methods in Molecular Biology ((MIMB,volume 681))

Abstract

The development of microfluidics and its utilization in a myriad of applications has grown exponentially over the past 15 years. One area that has benefited from the great strides in fabrication of microelectromechanical systems (MEMS) is separations chemistry. Most studies have focused on small molecule and DNA separations; few on protein chromatographic techniques on microchips. This review details recent developments in protein separations on microfluidic platforms and how MEMS have the potential for revolutionizing protein chromatography.

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Acknowledgments

The authors gratefully acknowledge financial support for this research by grants from the National Science Foundation (CHE-0515363 and DMR-0351848).

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Authors and Affiliations

  1. Department of Chemistry and Biochemistry, California State University, Los Angeles, CA, USA

    Frank A. Gomez

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  1. Frank A. Gomez
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Editors and Affiliations

  1. National Centre for Sensor Research, School of Biotechnology, Dublin City University, Dublin, 9, Ireland

    Dermot Walls

  2. National Centre for Sensor Research, School of Biotechnology, Dublin City University, Dublin, 9, Ireland

    Sinéad T. Loughran

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Gomez, F.A. (2011). Microfluidics in Protein Chromatography. In: Walls, D., Loughran, S. (eds) Protein Chromatography. Methods in Molecular Biology, vol 681. Humana Press. https://doi.org/10.1007/978-1-60761-913-0_8

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  • DOI: https://doi.org/10.1007/978-1-60761-913-0_8

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