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In Silico Prediction of Transcriptional Factor-Binding Sites

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In Silico Tools for Gene Discovery

Part of the book series: Methods in Molecular Biology ((MIMB,volume 760))

Abstract

The recognition of transcription factor binding sites (TFBSs) is the first step on the way to deciphering the DNA regulatory code. A large variety of computational approaches and corresponding in silico tools for TFBS recognition are available, each having their own advantages and shortcomings. This chapter provides a brief tutorial to assist end users in the application of these tools for functional characterization of genes.

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Author information

Authors and Affiliations

  1. Laboratory of Theoretical Genetics, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia

    Dmitry Y. Oshchepkov

  2. Laboratory of Theoretical Genetics, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia

    Victor G. Levitsky

Authors
  1. Dmitry Y. Oshchepkov
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  2. Victor G. Levitsky
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Corresponding author

Correspondence to Dmitry Y. Oshchepkov .

Editor information

Editors and Affiliations

  1. Royal Prince Alfred Hospital, Dept. of Molecular & Clinical Genetics, University of Sydney, Missenden Road, Camperdown, 2050, New South Wales, Australia

    Bing Yu

  2. Royal Prince Alfred Hospital, Dept. Molecular & Clinical Genetics, University of Sydney, Missenden Road, Camperdown, 2050, New South Wales, Australia

    Marcus Hinchcliffe

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Oshchepkov, D.Y., Levitsky, V.G. (2011). In Silico Prediction of Transcriptional Factor-Binding Sites. In: Yu, B., Hinchcliffe, M. (eds) In Silico Tools for Gene Discovery. Methods in Molecular Biology, vol 760. Humana Press. https://doi.org/10.1007/978-1-61779-176-5_16

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  • DOI: https://doi.org/10.1007/978-1-61779-176-5_16

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-61779-175-8

  • Online ISBN: 978-1-61779-176-5

  • eBook Packages: Springer Protocols

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