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In Vivo and In Vitro Studies on Peptide Release

  • Protocol
Peptides

Part of the book series: Neuromethods ((NM,volume 6))

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Abstract

The discovery that many peptide hormones previously identified in endocrine glands and/or in the endocrine brain (Hökfelt et al., 1980) are also present in central and peripheral neurons has unexpectedly increased the list of potential messengers participating in neuronal communication. To this list we must add other newly discovered peptides first detected as endogenous ligands of brain receptors (Hughes et al., 1975) and peptides whose existence was initially deduced from nucleotide or amino acid sequences in genes or protein precursors studied with the powerful techniques of modern molecular biology (Nakanishi et al., 1979; Lenoir et al., 1985). In order to understand the role of this growing list of peptides in neurohumoral coding of brain function, we must not only study the ways in which they interact with classical transmitter systems and modify the behavior of their target nerve cells, but also the ways in which they are produced, stored, and released.

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Author information

Authors and Affiliations

  1. Department of Molecular Biology, Instituto de Investigactones Biomedicas, Universtdad National Autonoma de Mexico and Analytical Neurochemistry Unit, Instituto Mexicano de Psiquiatria, Mexico City, Mexico

    Alejandro Bayón

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  1. Alejandro Bayón
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Editor information

Editors and Affiliations

  1. University of Saskatchewan, Canada

    Alan A. Boulton

  2. University of Alberta, Canada

    Glen B. Baker

  3. University of Calgary, Canada

    Q. J. Pittman

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© 1987 The Humana Press Inc.

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Bayón, A. (1987). In Vivo and In Vitro Studies on Peptide Release. In: Boulton, A.A., Baker, G.B., Pittman, Q.J. (eds) Peptides. Neuromethods, vol 6. Humana Press. https://doi.org/10.1385/0-89603-105-5:113

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  • DOI: https://doi.org/10.1385/0-89603-105-5:113

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-105-0

  • Online ISBN: 978-1-59259-611-9

  • eBook Packages: Springer Protocols

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