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Mapping of Genomic Clones by Fluorescence In Situ Hybridization

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Genomics Protocols

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 175))

Abstract

Fluorescence in situ hybridization (FISH) provides a rapid means of placing labeled DNA segments into a wider genomic context. Mapping to banded metaphase chromosomes anchors clones for specific genes or markers in a well-recognized framework and provides a useful confirmation that clones belong to the expected region of interest.

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© 2001 Humana Press Inc., Totowa, NJ

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Leversha, M.A. (2001). Mapping of Genomic Clones by Fluorescence In Situ Hybridization. In: Starkey, M.P., Elaswarapu, R. (eds) Genomics Protocols. Methods in Molecular Biology™, vol 175. Humana Press. https://doi.org/10.1385/1-59259-235-X:109

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  • DOI: https://doi.org/10.1385/1-59259-235-X:109

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-774-8

  • Online ISBN: 978-1-59259-235-7

  • eBook Packages: Springer Protocols

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