Abstract
The use of genetic approaches to study bacteria is limited by the following considerations: first, the bacteria must be easy to culture and nonpathogenic; and, second, a broad spectrum of genetic techniques for the particular bacteria being studied must be available. For other bacteria, such as the syphilis-causing spirochete, Treponema pallidum, genetic studies are highly limited because the bacterium cannot be continuously grown in the laboratory, because of its high virulence and a total lack of genetic tools to study this organism.
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© 2004 Humana Press Inc., Totowa, NJ
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Šmajs, D., Norris, S.J., Weinstock, G.M. (2004). Construction of Small Genome BAC Library for Functional and Genomic Applications. In: Zhao, S., Stodolsky, M. (eds) Bacterial Artificial Chromosomes. Methods in Molecular Biology™, vol 255. Humana Press. https://doi.org/10.1385/1-59259-752-1:047
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DOI: https://doi.org/10.1385/1-59259-752-1:047
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