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Comparative Genomics in C. elegans, C. briggsae, and Other Caenorhabditis Species

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C. elegans

Part of the book series: Methods in Molecular Biology ((MIMB,volume 351))

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Abstract

The genome of the nematode Caenorhabditis elegans was the first animal genome sequenced. Subsequent sequencing of the Caenorhabditis briggsae genome enabled a comparison of the genomes of two nematode species. In this chapter, we describe the methods that we used to compare the C. elegans genome to that of C. briggsae. We discuss how these methods could be developed to compare the C. elegans and C. briggsae genomes to those of Caenorhabditis remanei, C. n. sp. represented by strains PB2801 and CB5161, among others (1), and Caenorhabditis japonica, which are currently being sequenced.

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Author information

Authors and Affiliations

  1. Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Ireland

    Avril Coghlan

  2. Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

    Avril Coghlan

  3. Department of Molecular Genetics and Microbiology, Duke University, Durham, NC

    Jason E. Stajich

  4. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY

    Todd W. Harris

Authors
  1. Avril Coghlan
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  2. Jason E. Stajich
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  3. Todd W. Harris
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Editor information

Editors and Affiliations

  1. Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN

    Kevin Strange

  2. Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN

    Kevin Strange

  3. Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN

    Kevin Strange

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© 2006 Humana Press Inc.

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Coghlan, A., Stajich, J.E., Harris, T.W. (2006). Comparative Genomics in C. elegans, C. briggsae, and Other Caenorhabditis Species. In: Strange, K. (eds) C. elegans. Methods in Molecular Biology, vol 351. Humana Press. https://doi.org/10.1385/1-59745-151-7:13

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  • DOI: https://doi.org/10.1385/1-59745-151-7:13

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-597-2

  • Online ISBN: 978-1-59745-151-2

  • eBook Packages: Springer Protocols

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