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Optical Coherence Tomography: Advanced Modeling

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Handbook of Coherent Domain Optical Methods

Abstract

Analytical and numerical models for describing and understanding the light propagation in samples imaged by optical coherence tomography (OCT) systems are presented. An analytical model for calculating the OCT signal based on the extended Huygens-Fresnel principle valid both for the single and multiple scattering regimes is derived. An advanced Monte Carlo model for calculating the OCT signal is also derived, and the validity of this model is shown through a mathematical proof based on the extended Huygens-Fresnel principle. From the analytical model, an algorithm for enhancing OCT images is developed; the so-called true-reflection algorithm in which the OCT signal may be corrected for the attenuation caused by scattering. The algorithm is verified experimentally and by using the Monte Carlo model as a numerical tissue phantom. It is argued that the algorithm may improve interpretation of OCT images. Finally, the Wigner phase-space distribution function is derived in a closed-form solution, and on this basis a novel method of OCT imaging is proposed.

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Authors and Affiliations

  1. Optics and Fluid Dynamics Department, Risø National Laboratory, Roskilde, Denmark

    Peter E. Andersen, Lars Thrane, Andreas Tycho & Thomas M. Jørgensen

  2. Electronics and Photonics Laboratory, The Aerospace Corporation, Loas Angeles, CA, USA

    Harold T. Yura

Authors
  1. Peter E. Andersen
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  2. Lars Thrane
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  3. Harold T. Yura
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  4. Andreas Tycho
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  5. Thomas M. Jørgensen
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Editor information

Editors and Affiliations

  1. Precision Mechanics and Control Institute of the Russian Academy of Sciences, Saratov State University, Saratov, 410012, Russian Federation

    Valery V. Tuchin

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© 2004 Kluwer Academic Publishers

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Andersen, P.E., Thrane, L., Yura, H.T., Tycho, A., Jørgensen, T.M. (2004). Optical Coherence Tomography: Advanced Modeling. In: Tuchin, V.V. (eds) Handbook of Coherent Domain Optical Methods. Springer, New York, NY. https://doi.org/10.1007/0-387-29989-0_14

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  • DOI: https://doi.org/10.1007/0-387-29989-0_14

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