Virion
Morphology: |
Icosahedral |
Envelope: |
No |
Diameter (nm): |
28 |
Length (nm): |
– |
Structural components: |
RNA, capsid |
Buoyant density (g/mL): |
1.36 |
Buoyant density method: |
CsCl gradient |
Lipid composition: |
None |
Additional information: |
None |
Genome
Nucleic Acid: |
RNA |
|
Strandedness: |
Single-stranded |
|
Polarity: |
Positive-sense |
|
Configuration: |
Linear |
|
Segment organization: |
Segment no. 1 (kb): |
7.33 |
One segment(s): |
7.33 (kb) total (calculated) |
|
G + C content (%): |
39.1 |
|
mRNA transcripts: |
1 |
|
Open reading frames: |
1 |
|
Additional information: |
A single polyprotein is encoded and this is cleaved by virus proteases to give the final proteins (probably 10) |
Replication
Entry mechanism: |
Interactions between integrins avb1/avb3/avb6/avb8 and the virus RGD motif; subsequent endocytosis |
Site of transcription: |
n/a |
Transcriptase: |
n/a |
Site of genome replication: |
Cytoplasm, involving perinuclear replication complexes |
Replicase: |
Virus-encoded RNA-dependent RNA polymerase |
Replication intermediate: |
Negative sense RNA |
Site of virion... |
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Stanway, G., Williams, Ç.H., Hyypiä, T. (2011). Parechovirus. In: Tidona, C., Darai, G. (eds) The Springer Index of Viruses. Springer, New York, NY. https://doi.org/10.1007/978-0-387-95919-1_216
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DOI: https://doi.org/10.1007/978-0-387-95919-1_216
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