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Plasminogen Activator Inhibitor-1

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Encyclopedia of Signaling Molecules

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Synonyms

Plasminogen activator inhibitor; PAI; PAI-1; PAI1; PLANH1; Plasminogen activator inhibitor 1; Serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Serpin E1; Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; SERPINE1

BMAL-1 : ARNTL; Aryl Hydrocarbon Receptor Nuclear Translocator Like

Plasminogen activator inhibitor-2; PAI-2 : SERPINEB2; PLANH2; Plasminogen activator inhibitor-3; PAI-3: PCI; PLNH3; SERPINA5

tPA : tissue plasminogen acitvator, PLAT; Plasminogen Activator, Tissue Type

uPA : PLAU; Plasminogen Activator, urokinase-type plasminogen activator

Historical Background

The fibrinolysis complex includes a serine protease inhibitor (SERPIN), type-1 plasminogen activator inhibitor (PAI-1), and its target serine proteinases, the urokinase, and tissue-type plasminogen activators (uPA and tPA). As serine proteases, uPA and tPA coordinate various physiological functions,...

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Authors and Affiliations

  1. Department of Medical Biology, Acıbadem University School of Medicine, Istanbul, Turkey

    Deniz Agirbasli

  2. Department of Cardiology, Medeniyet University Medical Center, Istanbul, Turkey

    Mehmet Agirbasli

Authors
  1. Deniz Agirbasli
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  2. Mehmet Agirbasli
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Correspondence to Mehmet Agirbasli .

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Editors and Affiliations

  1. Dept. Biological Science, Department of Molecular Science and Tech College of Natural Science, Suwon, Korea (Republic of)

    Sangdun Choi

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Agirbasli, D., Agirbasli, M. (2017). Plasminogen Activator Inhibitor-1. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6438-9_101797-1

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