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HIV-2 Infection in Europe, Epidemiology of

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Encyclopedia of AIDS

Definition

The incidence of HIV-2 infection shows signs of decline in the endemic regions of West Central Africa, while HIV-1 infection continues its pandemic global spread (Silva et al. 2008).

The HIV-2 epidemic remains largely confined to West Africa, where it peaked in prevalence in the 1970s and 1980s, with an epicenter in and around Guinea Bissau (Fig. 1).

Fig. 1
figure 1

HIV-2 infection prevalence in West Africa: Pink areas: HIV-2 predominant; Blue areas: HIV-2 and HIV-1 in the same proportion; Yellow areas: HIV-2 less frequent (Caroline D et al. Science et vie 1992;179:38–41)

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References

  • Barin F, Cazein F, Lot F, Pillonel J, Brunet S, Thierry D, Damond F, Brun-Vézinet F, Desenclos JC, Semaille C. Prevalence of HIV-2 and HIV-1 group O infections among new HIV diagnoses in France: 2003–2006. AIDS. 2007;21(17):2351–3.

    Article  PubMed  Google Scholar 

  • Bock PJ, Markovitz DM. Infection with HIV-2. AIDS. 2001;15(S5):S35–45.

    Article  CAS  PubMed  Google Scholar 

  • Campbell-Yesufu OT, Gandhi RT. Update on Human Immunodeficiency Virus (HIV)-2 infection. Clin Infect Dis. 2011;52(6):780–7.

    Article  PubMed  PubMed Central  Google Scholar 

  • Carvalho AC, Valadas E, França L, Carvalho C, Aleixo MJ, Mendez J, Marques R, Sarmento A, Doroana M, Antunes F, Branco T, Águas M, Sarmento e Castro R, Lazarus JV, Barros H. Population mobility and the changing epidemics of HIV-2 in Portugal. HIV Med. 2011. doi:10.1111/j.1468-1293.2011.00963.x.

    PubMed  Google Scholar 

  • Clavel F, Mansinho K, Chamaret S, Guetard D, Favier V, Nina J, Santos-Ferreira MO, Champalimaud JL, Montagnier L. Human Immunodeficiency Virus Type 2 infection associated with AIDS in West Africa. N Engl J Med. 1987;316(19):1180–5.

    Article  CAS  PubMed  Google Scholar 

  • Costarelli S, Torti C, Rodella A, Baldanti F, Paolucci S, Lapadula G, Manca N, Quiros-Roldan E, Izzo I, Carosi G. Screening and management of HIV-2-infected individuals in Northern Italy. AIDS Patient Care STDS. 2007;22(6):489–94.

    Article  Google Scholar 

  • Damond F, Apetrei C, Robertson DL, Souquière S, Leprêtre A, Matheron S, Plantier JC, Brun-Vézinet F, Simon F. Variability of Human Immunodeficiency Virus Type 2 (HIV-2) infecting patients living in France. Virology. 2001;280:19–30.

    Article  CAS  PubMed  Google Scholar 

  • Damond F, Benard A, Balotta C, Boni J, Cotton M, Duque V, Ferns B, Garson J, Gomes P, Gonçalves F, Gottlieb G, Kupfer B, Ruelle J, Rodes B, Soriano V, Wainberg M, Taieb A, Matheron S, Chene G, Brun-Vezimet F, ACHIEV2E Study Group. An international collaboration to standardize HIV-2 viral load assays: results from the 2009 ACHIEV2E Quality Control Study. J Clin Microbiol. 2011;49(10):3491–7.

    Google Scholar 

  • Dougan S, Patel B, Tosswill JH, Sinka K. Diagnoses of HIV-1 and HIV-2 in England, Wales, and Northen Ireland associated with West Africa. Sex Transm Infect. 2005;81:338–41.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Esbjornsson J, Mansson F, Kvist A, Isberg PE, Nowroozalizadeh S, Biague AJ, Da Silva ZJ, Jansson M, Fenyo EM, Norrgren H, Medstrand P. Inhibition of HIV-1 disease progression by contemporaneous HIV-2 infection. N Engl J Med. 2012;367:224–32.

    Article  PubMed  Google Scholar 

  • Hahn BH, Shaw GM, De Cock KM, Sharp PM. AIDS as a zoonosis: scientific and public health implications. Science. 2000;287:607–14.

    Article  CAS  PubMed  Google Scholar 

  • Lemey P, Pybus OG, Wang B, Saksena NK, Salemi M, Vandamme AM. Tracing the origin and history of the HIV-2 epidemic. Proc Natl Acad Sci U S A. 2003;100(11):6588–92.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Markovitz DM. Infection with the Human Immunodeficiency Virus Type 2. Ann Intern Med. 1993;118:211–8.

    Article  CAS  PubMed  Google Scholar 

  • Peeters M, Jung M, Ayouba A. The origin and molecular epidemiology of HIV. Expert Rev Anti Infect Ther. 2013;11(9):885–96.

    Article  CAS  PubMed  Google Scholar 

  • Sharp PM, Hahn BH. Origins of HIV and the AIDS Pandemic. Cold Spring Harb Perspect Med. 2011;1:a006841.

    Article  PubMed  PubMed Central  Google Scholar 

  • Silva TI, Cotton M, Rowland-Jones SL. HIV-2: the forgotten AIDS virus. Trends Microbiol. 2008;16(12):588–95.

    Article  PubMed  Google Scholar 

  • Soriano V, Gomes P, Heneine W, Holguín A, Doroana M, Antunes R, Mansinho K, Switzer WM, Araújo C, Shanmugam V, Lourenço H, González-Lahoz J, Antunes F. Human Immunodeficiency Virus Type 2 (HIV-2) in Portugal: clinical spectrum, circulation subtypes, virus isolation and plasma viral load. J Med Virol. 2000;61:111–6.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Ana Cláudia Miranda .

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Miranda, A.C., Mansinho, K. (2016). HIV-2 Infection in Europe, Epidemiology of. In: Hope, T., Richman, D., Stevenson, M. (eds) Encyclopedia of AIDS. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9610-6_42-1

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