Definition
A nonheritable developmental disease resulting of abnormal metanephric differentiation.
Clinical Features
Incidence
It occurs in 1 in 4300 live births. Multicystic dysplastic kidneys are also a finding of genetic disorders (Sanna-Cherchi et al. 2007).
Age
It is a congenital urinary tract anomaly (Bernstein 1971).
Sex
Multicystic renal dysplasia affects predominantly males.
Site
The condition is usually unilateral.
Treatment
Although previously, nephrectomy was the treatment of choice to avoid potential complications such as infection, pain, hypertension, and malignancy, to date the management is primarily conservative.
Outcome
Most patients have a favorable prognosis.
Multicystic renal dysplasia is usually sporadic but may rarely be associated with obstruction, multi-malformation syndromes, chromosomal anomalies, or hereditary malformation syndromes. Unilateral multicystic renal dysplasia is the most common cause of renal mass in childhood. Bilateral lesions may be present...
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References and Further Reading
Bernstein, J. (1971). The morphogenesis of renal parenchymal maldevelopment (renal dysplasia). Pediatric Clinics of North America, 18, 395ā407.
Sanna-Cherchi, S., Caridi, G., Weng, P. L., et al. (2007). Genetic approaches to human renal agenesis/hypoplasia and dysplasia. Pediatric Nephrology, 22, 1675ā1684.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
Ā© 2020 Springer Nature Switzerland AG
About this entry
Cite this entry
CaliĆ², A., Segala, D., Martignoni, G. (2020). Multicystic Renal Dysplasia. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_4854
Download citation
DOI: https://doi.org/10.1007/978-3-030-41894-6_4854
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-41893-9
Online ISBN: 978-3-030-41894-6
eBook Packages: MedicineReference Module Medicine