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Teratoma, Prepubertal-Type

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Uropathology

Part of the book series: Encyclopedia of Pathology ((EP))

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Synonyms

Benign postpubertal testicular teratoma; Dermoid cyst; Type I germ cell tumor of the testis

Definition

A tumor usually seen in the prepubertal testis (but it encompasses all age groups) composed of tissue derived from one or more of different germinal layers.

Clinical Features

  • Incidence

    Teratomas are, after YST, the second most frequent (14–20%) GCT in infancy.

  • Age

    This tumor occurs before puberty, while when occurring in older patients they may have been present but undiagnosed since childhood. They typically occur before the age of 6 years, the oldest reported patient being 59 years with an average age of 20 months.

  • Site

    Testis.

  • Treatment

    Conservative treatment is appropriate.

  • Outcome

    Actually no documented cases have exhibited malignant behavior (Zhang et al. 2013). The exception is carcinoid tumor that has a metastatic potential.

Macroscopy

Grossly prepubertal-type teratoma occurs as a solid nodule or with a cystic component filled with keratinous (Fig. 1) or mucoid...

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References and Further Reading

  • Ulbright, T. M., & Srigley, J. R. (2001). Dermoid cyst of the testis: A study of five postpubertal cases, including a pilomatrixoma-like variant, with evidence supporting its separate classification from mature testicular teratoma. The American Journal of Surgical Pathology, 25(6), 788–793.

    Article  CAS  Google Scholar 

  • Wang, W. P., Guo, C., Berney, D. M., Ulbright, T. M., Hansel, D. E., Shen, R., Ali, T., & Epstein, J. I. (2010). Primary carcinoid tumors of the testis: A clinicopathologic study of 29 cases. The American Journal of Surgical Pathology, 34(4), 519–524.

    Article  Google Scholar 

  • Zhang, C., Berney, D. M., Hirsch, M. S., Cheng, L., & Ulbright, T. M. (2013). Evidence supporting the existence of benign teratomas of the postpubertal testis: A clinical, histopathologic, and molecular genetic analysis of 25 cases. The American Journal of Surgical Pathology, 37(6), 827–835.

    Article  Google Scholar 

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Correspondence to Maurizio Colecchia .

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Colecchia, M., Bertolotti, A. (2020). Teratoma, Prepubertal-Type. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_4957

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  • DOI: https://doi.org/10.1007/978-3-030-41894-6_4957

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-41893-9

  • Online ISBN: 978-3-030-41894-6

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