Skip to main content
SpringerLink
Log in

Urinary Tract Villous Adenoma

  • Living reference work entry
  • First Online:
Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

  • 21 Accesses

Synonyms

Villous adenoma

Definition

Benign exophytic glandular tumor.

Clinical Features

  • Incidence

    It is a rare tumor which arises from a metaplastic process of the urothelium.

  • Age

    It occurs mainly in elderly patients: mean age 65 years, range 23–94.

  • Sex

    There is reported a male predominance.

  • Site

    The urachus and the bladder dome and the trigone are the most common site.

  • Treatment

    The treatment is surgical excision of the tumor.

  • Outcome

    Prognosis is excellent; however the progression to adenocarcinoma has been reported in 20% of the cases when the lesion has not been completely resected.

Macroscopy

Grossly, it appears as an exophytic lesion.

Microscopy

Histological findings of villous adenoma in the urinary tract, which are the same of villous adenoma in the intestinal tract, include a delicate fibrovascular stalk lined with columnar cells (Fig. 1). The cells may present crowding, hyperchromasia, and prominent nucleoli with pseudostratified nuclei and uncommon non-atypical mitoses. The...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

References and Further Reading

  • Channer, J. L., Williams, J. L., & Henry, L. (1993). Villous adenoma of the bladder. Journal of Clinical Pathology, 46, 450–452.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Cheng, L., Montironi, R., & Bostwick, D. G. (1999). Villous adenoma of the urinary bladder: A report of 23 cases, including 8 with coexistent adenocarcinoma. The American Journal of Surgical Pathology, 23, 764–771.

    Article  CAS  PubMed  Google Scholar 

  • Seibel, J. L., Prasad, S., Weisse, R. E., et al. (2002). Villous adenoma of the urinary bladder: A lesion frequently associated with malignancy. Human Pathology, 33, 236–241.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Histopathology and Molecular Diagnostics, University Hospital Careggi, Florence, Italy

    Maria Rosaria Raspollini

  2. Pathology Service, Champalimaud Clinical Center, Lisbon, Portugal

    Antonio Lopez-Beltran

  3. Unit of Anatomic Pathology, Department of Surgery, Cordoba University Medical School, Cordoba, Spain

    Antonio Lopez-Beltran

Authors
  1. Maria Rosaria Raspollini
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Antonio Lopez-Beltran
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Maria Rosaria Raspollini .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Raspollini, M.R., Lopez-Beltran, A. (2020). Urinary Tract Villous Adenoma. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4977-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-28845-1_4977-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation