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Disseminated Peritoneal Leiomyomatosis (Leiomyomatosis Peritonealis Disseminata)

  • Living reference work entry
  • First Online:
Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

  • 20 Accesses

Definition

A disorder characterized by multiple, often numerous, banal-appearing smooth muscle neoplasms involving the peritoneal and abdominal cavity.

Clinical Features

  • Incidence

    Disseminated peritoneal leiomyomatosis is uncommon and often discovered incidentally. Most (>70%) occur in women who are currently or recently pregnant or who are on oral contraception. Rarely, it occurs in the setting of an estrogen-producing ovarian tumor. This condition may also occur following unconfined morcellation of otherwise benign uterine leiomyomata.

  • Age

    Patients are typically reproductive aged, but occasionally this disorder can occur in postmenopausal women.

  • Sex

    This condition occurs in women.

  • Site

    Tumors typically involve surfaces of the peritoneal and abdominal cavity.

  • Treatment

    Persistent and unresectable disease has been successfully treated with gonadotropin-releasing hormone agonists or aromatase inhibitors.

  • Outcome

    Patients typically have a benign clinical course and aggressive...

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References and Further Reading

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Author information

Authors and Affiliations

  1. Division of Women’s and Perinatal Pathology, Department of Pathology, Brigham Women’s Hospital, Boston, MA, USA

    Marisa R. Nucci

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  1. Marisa R. Nucci
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Correspondence to Marisa R. Nucci .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Nucci, M.R. (2020). Disseminated Peritoneal Leiomyomatosis (Leiomyomatosis Peritonealis Disseminata). In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_5415-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_5415-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

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