Synonyms
Acute infantile hemorrhagic edema; Allergic vasculitis; Anaphylactoid purpura; Cutaneous leukocytoclastic angiitis; Hypersensitivity vasculitis/angiitis; Necrotizing vasculitis
Definition
In the assessment of a patient with cutaneous vasculitis, clinicians and pathologists must deal with many challenges that include classifying the vasculitis syndrome; assessing for extent of systemic disease; confirming diagnosis; identifying triggers, causes, or associated diseases; and initiating effective therapy. The majority of cutaneous vasculitis patients will show a neutrophilic small-vessel vasculitis, also known as leukocytoclastic vasculitis (LCV), which is not a diagnosis in itself, but rather a histologic pattern that generates a broad differential diagnosis of vasculitic syndromes. The clinical and histologic findings of LCV are the same whether it represents an idiopathic, self-limited, localized cutaneous vasculitis (e.g., cutaneous leukocytoclastic angiitis (CLA)) or a...
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References and Further Reading
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Raghu, P.R., Carlson, J.A. (2016). Cutaneous Leukocytoclastic Vasculitis (LCV). In: Massi, D. (eds) Dermatopathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-30006-1_439
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DOI: https://doi.org/10.1007/978-3-319-30006-1_439
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