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Secondary Craniosynostoses

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Textbook of Pediatric Neurosurgery

Abstract

Craniosynostoses can be divided generally into primary and secondary ones. Although majority of craniosynostosis cases are of genetic origin (primary synostoses), a small number results from other causes, particularly metabolic, hematologic, or drug-related disorders. In some cases synostosis may occur as a consequence to overdrainage in children treated with shunts for hydrocephalus. A specific situation is microcephaly resulting from early sutures closure associated with failure of brain growth. The various aspects of the secondary craniosynostosis are presented and discussed in the chapter.

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References

  • Al-Tamimi YZ, Tyagi AK, Chumas PD et al (2008) Patients with autosomal-recessive osteopetrosis presenting with hydrocephalus and hindbrain posterior fossa crowding. J Neurosurg Pediatr 1:103–106

    Article  PubMed  Google Scholar 

  • Andersson H (1966) Craniosynostosis as a complication after operation for hydrocephalus. Acta Pediatr Scand 55:192

    Article  Google Scholar 

  • Benichou OD, Laredo JD, de Vernejoul MC (2000) Type II autosomal dominant osteopetrosis (Albers-Schonberg disease): clinical and radiological manifestations in 42 patients. Bone 26:87–93

    Article  CAS  PubMed  Google Scholar 

  • Bollerslev J, Andersen PE Jr (1988) Radiological, biochemical and hereditary evidence of two types of autosomal dominant osteopetrosis. Bone 9:7–13

    Article  CAS  PubMed  Google Scholar 

  • Brisman JL, Niimi Y, Berenstein A (2004) Sinus pericranii involving the torcular sinus in a patient with Hunter’s syndrome and trigonocephaly: case report and review of the literature. Neurosurgery 55:433

    Article  PubMed  Google Scholar 

  • Carmichael SL, Clarke CM, Cunningham ML (2015) Craniosynostosis: the potential contribution of thyroid-related mechanisms. Curr Epidemiol Rep 2:1–7

    Article  Google Scholar 

  • Currarino G (2007) Sagittal synostosis in X-linked hypophosphatemic rickets and related diseases. Pediatr Radiol 37:805–812

    Article  PubMed  Google Scholar 

  • Davis C, Lauritzen CGK (2008) Spring-assisted remodeling for ventricular shunt-induced cranial deformity. J Craniofac Surg 19:588–592

    Article  PubMed  Google Scholar 

  • Doorenbosch X, Molloy CJ, David DJ et al (2009) Management of cranial deformity following ventricular shunting. Childs Nerv Syst 25:871–874

    Article  CAS  PubMed  Google Scholar 

  • Dowlati D, Winston KR, Ketch LL et al (2007) Expansion cranioplasty with jackscrew distracters for craniosynostosis and intracranial hypertension in transplanted osteopetrosis. Pediatr Neurosurg 43:102–106

    Article  PubMed  Google Scholar 

  • Faulhauer K, Schmitz P (1978) Overdrainage phenomena in shunt treated hydrocephalus. Acta Neurochir (Wien) 45:89–101

    Article  CAS  Google Scholar 

  • Freudlsperger C, Hoffmann J, Castrillion-Oberndorfer G (2013) Bilateral coronal and sagittal synostosis in X-linked hypophosphatemic rickets: a case report. J Craniomaxillofac Surg 41:842–844

    Article  PubMed  Google Scholar 

  • Garg R, Khanna P, Pandia M (2010) Anaesthetic considerations in a child with rickets and craniosynostosis for linear strip craniectomy and frontal advancement. Indian J Anaesth 54:350–351

    Article  PubMed  PubMed Central  Google Scholar 

  • Glass LR, Dagi TF, Dagi LR (2011) Papilledema in the setting of x- linked hypophosphatemic rickets with craniosynostosis. Case Rep Ophthalmol 2:376–381

    Article  PubMed  PubMed Central  Google Scholar 

  • Grabb PA, Albright L, Zitelli BJ (1995) Multiple suture synostosis, macrocephaly, and intracranial hypertension in a child with alpha-D-mannosidase deficiency. J Neurosurg 82:647–649

    Article  CAS  PubMed  Google Scholar 

  • Hashmi SS, Canfield MA, Marengo L et al (2012) The association between neonatal thyroxine and craniosynostosis, Texas, 2004–2007. Birth Defects Res A Clin Mol Teratol 94:1004–1009

    Article  CAS  PubMed  Google Scholar 

  • Heschl M (1873) Einige Bemerkunger über Föntale und prä-mature obliterationen der Schädelnähte. Vjscher Prakt Heilk 120:135

    Google Scholar 

  • Higashino T, Hirabayashi S (2013) A secondary craniosynostosis associated with juvenile hyperthyroidism. J Plast Reconstr Aesthet Surg 66:e284–e286

    Article  PubMed  Google Scholar 

  • Immerslund O (1951) Craniostenosis and vitamin D-resistant rickets. Acta Pediatr 40:449–451

    Article  Google Scholar 

  • Jaszczuk P, Rogers GF, Guzman R et al (2016) X-linked hypophosphatemic rickets and sagittal craniosynostosis: three patients requiring operative cranial expansion: case series and literature review. Childs Nerv Syst 32:857–891

    Article  Google Scholar 

  • Johnsonbaugh RE, Bryan RN, Hierlwimmer R et al (1978) Premature craniosynostosis: a common complication of juvenile thyrotoxicosis. J Pediatr 93:188–191

    Article  CAS  PubMed  Google Scholar 

  • Jonsson KB, Zahradnik R, Larsson T (2003) Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia. N Engl J Med 348:1656–1663

    Article  CAS  PubMed  Google Scholar 

  • Krimmel M, Niemann G, Reinert S (2004) Surgical correction of craniosynostosis in malignant osteopetrosis. J Craniofac Surg 15:218–220

    Article  PubMed  Google Scholar 

  • Lachman R, Martin KW, Castro S et al (2010) Radiologic and neuroradiologic findings in the mucopolysaccharidoses. J Pediatr Rehabil Med 3:109–118

    PubMed  Google Scholar 

  • Loop JW, Foltz EL (1972) Craniostenosis and diploic lamination following operation for hydrocephalus. Acta Radiol Diagn 13:8–13

    Article  CAS  Google Scholar 

  • Loria-Cortes R, Quesada-Calvo E, Cordero-Chaverri C (1977) Osteopetrosis in children: a report of 26 cases. J Pediatr 91:43–47

    Article  CAS  PubMed  Google Scholar 

  • Lowdon J (2011) Rickets: concerns over the worldwide increase. J Fam Health Care 21:25–29

    PubMed  Google Scholar 

  • Manara R, Priante E, Grimaldi M et al (2011) Brain and spine MRI features of Hunter disease: frequency, natural evolution and response to therapy. J Inherit Metab Dis 34:763–780

    Article  PubMed  Google Scholar 

  • Martínez-Lage JF, Ruiz-Espejo Vllar A, Pérez-Espejo MA et al (2006) Shunt-related craniocerebral disproportion: treatment with cranial vault expanding procedures. Neurosurg Rev 29:229–235

    Article  PubMed  Google Scholar 

  • Murthy AS (2009) X-linked hypophosphatemic rickets and craniosynostosis. J Craniofac Surg 20:439–442

    Article  PubMed  Google Scholar 

  • Nilsson D, Svensson J, Korkmaz BA et al (2013) Decreased head circumference in shunt-treated compared with healthy children. J Neurosurg Pediatr 12:483–490

    Article  PubMed  Google Scholar 

  • Park DH, Chung J, Yoon SH (2009) The role of distraction osteogenesis in children with secondary craniosynostosis after shunt operation in early infancy. Pediatr Neurosurg 45:437–445

    Article  PubMed  Google Scholar 

  • Pudenz RH, Foltz EL (1991) Hydrocephalus: overdrainage by ventricular shunts. A review and recommendations. Surg Neurol 35:200–212

    Article  CAS  PubMed  Google Scholar 

  • Rasmussen SA, Yazdy MM, Carmichael SL et al (2007) Maternal thyroid disease as a risk factor for craniosynostosis. Obstet Gynecol 110:369–377

    Article  PubMed  Google Scholar 

  • Reilly BJ, Leeming JM, Fraser D (1964) Craniosynostosis in the rachitic spectrum. J Pediatr 64:396–405

    Article  CAS  PubMed  Google Scholar 

  • Roberts JR, Rickham PP (1970) Craniostenosis following Holter valve operation. Dev Med Child Neurol 12(Suppl 22):145–149

    Google Scholar 

  • Seruya M, Oh AK, Boyajian MJ (2013) Age at initial consultation for craniosynostosis: comparison across different patient characteristics. J Craniofac Surg 24:96–98

    Article  PubMed  Google Scholar 

  • Shimada T, Hasegawa H, Yamazaki Y et al (2004) FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis. J Bone Miner Res 19:429–435

    Article  CAS  PubMed  Google Scholar 

  • Shuster BA, Norbash AM, Schendel SA (1995) Correction of scaphocephaly secondary to ventricular shunting procedures. Plast Reconstr Surg 96:1012–1019

    Article  CAS  PubMed  Google Scholar 

  • Spranger J, Gehler J, Cantz M (1976) The radiographic features of mannosidosis. Radiology 119:401–407

    Article  CAS  PubMed  Google Scholar 

  • Stamper BD, Mecham B, Park SS et al (2012) Transcriptome correlation analysis identifies two unique craniosynostosis subtypes associated with IRS1 activation. Physiol Genomics 44:1154–1163

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Stark Z, Savarirayan R (2009) Osteopetrosis. Orphanet J Rare Dis 4:5

    Article  PubMed  PubMed Central  Google Scholar 

  • Tamburrini G, Caldarelli M, Massimi L et al (2005) Intracranial pressure monitoring in children with single suture and complex craniosynostosis: a review. Childs Nerv Syst 21:913–921

    Article  CAS  PubMed  Google Scholar 

  • Vega RA, Opalak C, Harshbarger RJ et al (2016) Hypophosphatemic rickets and craniosynostosis: a multicenter case series. J Neurosurg Pediatr 17:694–700

    Article  PubMed  Google Scholar 

  • Wang PI, Marcus JR, Fuchs HE et al (2015) Craniosynostosis secondary to rickets: manifestations on computed tomography. Radiol Case Rep 2:43

    Article  PubMed  PubMed Central  Google Scholar 

  • Weinzweig J, Bartlett SP, Chen JC et al (2008) Cranial vault expansion in the management of postshunt craniosynostosis and slit ventricle syndrome. Plast Reconstr Surg 122:1171–1180

    Article  CAS  PubMed  Google Scholar 

  • Willis FR, Beattie TJ (1997) Craniosynostosis in X-linked hypophosphataemic rickets. J Paediatr Child Health 33:78–79

    Article  CAS  PubMed  Google Scholar 

  • Wilson CJ, Vellodi A (2000) Autosomal recessive osteopetrosis: diagnosis, management, and outcome. Arch Dis Child 83:449–452

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wilson S, Hashamiyan S, Clarke L et al (2009) Glycosaminoglycan-mediated loss of cathepsin K collagenolytic activity in MPS I contributes to osteoclast and growth plate abnormalities. Am J Pathol 175:2053–2062

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ziyadeh J, Le Merrer M, Robert M et al (2013) Mucopolysaccharidosis type I and craniosynostosis. Acta Neurochir 155:1973–1976

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Paediatric Neurosurgery, School of Public Health, Medical University of Silesia, ul. Medyków 16, Katowice, 40-752, Poland

    Marek Mandera

Authors
  1. Marek Mandera
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Correspondence to Marek Mandera .

Editor information

Editors and Affiliations

  1. International Neuroscience Institute, Hannover, Germany

    Concezio Di Rocco

  2. Oakland Medical Center, Oakland, California, USA

    Dachling Pang

  3. University of Toronto Hospital for Sick Children, Toronto, Ontario, Canada

    James T. Rutka

Section Editor information

  1. Director of Pediatric Neurosurgery, International Neuroscience Institute, Hannover, Germany

    Concezio Di Rocco

  2. University of Paris, Paris, France

    Rocco, F Di

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Mandera, M. (2017). Secondary Craniosynostoses. In: Di Rocco, C., Pang, D., Rutka, J. (eds) Textbook of Pediatric Neurosurgery. Springer, Cham. https://doi.org/10.1007/978-3-319-31512-6_64-1

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  • DOI: https://doi.org/10.1007/978-3-319-31512-6_64-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-31512-6

  • Online ISBN: 978-3-319-31512-6

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