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Glomus Tumor, Gastrointestinal

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  • First Online:
Pathology of the Gastrointestinal Tract

Part of the book series: Encyclopedia of Pathology ((EP))

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Synonyms

Glomangioma; Glomangiomatosis; Glomangiomyoma; Glomangiopericytoma; Glomangiosarcoma; Malignant glomus tumor; Symplastic glomus tumor

Definition

Glomus tumors are mesenchymal neoplasm comprising cells that resemble the modified smooth muscle cells of the normal glomus body. The glomus body is a specialized form of arteriovenous anastomosis which is involved in temperature regulation. There is a central coiled canal known as Sucquet-Hoyer canal which is lined by plump endothelial cells. This is surrounded by longitudinal and circular muscle fibers containing epithelial appearing glomus cells.

Clinical Features

  • Incidence

    Glomus tumors are rare in the gastrointestinal tract. The incidence of glomus tumor is estimated to be 1% of that of gastrointestinal tumors.

  • Age

    The median age of gastrointestinal glomus tumors is 48–55 years (range 19–90 years) (Kang et al. 2012).

  • Sex

    Gastrointestinal glomus tumors predominate in females (∼ 3:1) (Miettinnen et al. 2010).

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References and Further Reading

  • Kang, G., Park, H. P., Kim, J. Y., Choi, D., Min, B. H., Lee, J. H., Kim, J. J., Kim, K.-M., Park, C. K., Sohn, T. S., & Kim, S. (2012). Glomus tumor of the stomach: A clinicopathologic analysis of 10 cases and review of the literature. Gut and Liver, 6, 52–57.

    PubMed  PubMed Central  Google Scholar 

  • Miettinen, M., Paal, E., Lasota, J., & Sobin, L. H. (2002). Gastrointestinal glomus tumors: A clinicopathologic, immunohistochemical, and molecular genetic study of 32 cases. American Journal of Surgical Pathology, 26, 301–311.

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  • Miettinnen, M. (2010). Glomus tumor, sinonasal haemangiopericytoma, and myopericytoma. In M. Miettinen (Ed.), Modern soft tissue pathology: Tumors and non-neoplastic conditions (pp. 648–656). Cambridge: Cambridge University Press.

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  • Miettinnen, M., Fletcher, C. D. M., Kindblom, L.-G., & Tsui, W. M. S. (2010). Mesenchymal tumours of the oesophagus, stomach, small intestine, colon and rectum. In F. T. Bosman, F. Carneiro, R. H. Hruban, & N. E. Theise (Eds.), WHO classification of tumours of the digestive system (p. 76). Lyon: International Agency for Research on Cancer (IARC).

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Author information

Authors and Affiliations

  1. Faculty of Medicine of the University of Porto and Institute of Molecular Pathology and Immunology of the University of Porto, Rua Dr. Roberto Frias S/N, 4200-465, Porto, Portugal

    José Manuel Lopes

Authors
  1. José Manuel Lopes
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Corresponding author

Correspondence to José Manuel Lopes .

Editor information

Editors and Affiliations

  1. Faculty of Medicine of Porto University, Centro Hospitalar São João and Ipatimup/i3S, Porto, Portugal

    Fátima Carneiro

  2. Serviço de Anatomia Patológica, Instituto Português de Oncologia de Lisboa de Francisco Gentil, Lisbon, Portugal

    Paula Chaves

  3. Faculdade de Ciências da Saúde, Universidade da Beira Interior, Covilhã, Portugal

    Paula Chaves

  4. Department of Pathology, Ankara University Medical School, Sihhiye, Ankara, Turkey

    Arzu Ensari

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Lopes, J.M. (2017). Glomus Tumor, Gastrointestinal. In: Carneiro, F., Chaves, P., Ensari, A. (eds) Pathology of the Gastrointestinal Tract. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-40560-5_1625

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  • DOI: https://doi.org/10.1007/978-3-319-40560-5_1625

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-40559-9

  • Online ISBN: 978-3-319-40560-5

  • eBook Packages: MedicineReference Module Medicine

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