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Acidosis

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Encyclopedia of Pain

Definition

Acidosis is the disturbance of the acid-base balance, characterized by acidity (decreased pH) by accumulation of protons, caused by injury, inflammation or ischemia. Acidosis is an important source of pain. In humans, it produces non-adapting nociceptor excitation and contributes to hyperalgesia and allodynia in inflammation.

Acid-Sensing Ion Channels

TRPV1, Regulation by Protons

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© 2007 Springer-Verlag Berlin Heidelberg

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(2007). Acidosis. In: Schmidt, R., Willis, W. (eds) Encyclopedia of Pain. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-29805-2_34

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  • DOI: https://doi.org/10.1007/978-3-540-29805-2_34

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-43957-8

  • Online ISBN: 978-3-540-29805-2

  • eBook Packages: MedicineReference Module Medicine

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