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Papillomas, Conjunctival

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Encyclopedia of Ophthalmology

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Synonyms

Conjunctival squamous cell papilloma

Definition

Conjunctival papillomas are benign squamous epithelial growths of viral origin (human papillomavirus) with limited tendency toward malignancy (Bailey and Guethlein 1990). They may develop from the bulbar or palpebral conjunctiva. They are categorized as infectious, squamous, limbal, or inverted based upon clinical and patient history. They may also be classified according to gross appearance as either pedunculated or sessile.

Etiology

Infectious squamous conjunctival papillomas have a strong association with human papillomavirus (HPV) types 6 and 11 (Minchiotti et al. 2006). HPV is transmitted via direct human contact and typically produces benign tumor growths with minimal risk for malignancy. HPV 33 is also associated with conjunctival papillomas. The recurrence rate for conjunctival papillomas of viral etiology is quite high; limbal papillomas have a 40 % recurrence rate.

Noninfectious causes of conjunctival papillomas may...

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References

  • Bailey RN, Guethlein ME (1990) Diagnosis and management of conjunctival papillomas. J Am Optom Assoc 61(5):405–412

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  • Eagle RC (1999) Chapter 4. Conjunctiva. In: Eye pathology – an atlas and basic text. WB Saunders, Philadelphia, pp 47–48, 59, 61–62

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  • Minchiotti S, Masucci L, Serapiao Dos Santos M, Perrella E, Graffeo R, Lambiase A (2006) Conjunctival papilloma and human papillomavirus: identification of HPV types by PCR. Eur J Ophthalmol 16(3):473–477

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  • Omohundro JM, Elliott JH (1970) Cryotherapy of conjunctival papilloma. Arch Ophthalmol 84(5):609–610

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  • Schechter BA, Rand WJ, Velazquez GE et al (2002) Treatment of conjunctival papillomata with topical interferon Alfa-2b. Am J Ophthalmol 134(2):268–270

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Author information

Authors and Affiliations

  1. Johns Hopkins University School of Medicine, 8369 Tamar Dr, Apt 731, Baltimore, MD, 21045, USA

    Sidharth Puri

Authors
  1. Sidharth Puri
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Correspondence to Sidharth Puri .

Editor information

Editors and Affiliations

  1. Dept of Ophthal & Optometry,AKH, Medical University of Wien Dept of Ophthal & Optometry,AKH, Wien, Austria

    Ursula Schmidt-Erfurth

  2. Department of Ophthalmology, Goethe University of Frankfurt am Main Department of Ophthalmology, Frankfurt am Main, Germany

    Thomas Kohnen

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© 2014 Springer-Verlag Berlin Heidelberg

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Puri, S. (2014). Papillomas, Conjunctival. In: Schmidt-Erfurth, U., Kohnen, T. (eds) Encyclopedia of Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35951-4_540-2

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  • DOI: https://doi.org/10.1007/978-3-642-35951-4_540-2

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-35951-4

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